Variations in behavior, innate immunity and host resistance to B16F10 melanoma growth in mice that present social stable hierarchical ranks

Physiology & Behavior
V M Sá-RochaJ Palermo-Neto

Abstract

The present study analyzed the effect of social stable hierarchical dominance/submissive relationships in C57BL/6 mice on behavior, innate immunity, serum corticosterone levels and host resistance to B16F10 melanoma growth. Adult mice (90 days old) kept in pairs since weaning, were analyzed for dominant/submissive ranking in three consecutive days according to the presence or absence of fighting and/or anticipatory submissive responses. Only the pairs of mice where dominant/submissive relationships were clearly stated were employed. Results showed that submissive mice presented in relation to dominants: (1) decreased time spent in the central open-field area; (2) decreased number of entries into the open arms and decreased time spent in the exploration of the open arms of the plus maze; (3) increased time spent in exploration of the plus-maze closed arms; (4) decreased number of entries and in the time spent in the exploration of the third part of the plus-maze open arms; (5) increased number of B16F10 metastasis in the lungs; (6) decreased NK cell cytotoxicity measured in vitro in the peripheral blood and spleen; (7) decreased basal but not in S. aureus induced oxidative burst in both neutrophils and monocytes and (8) similar ...Continue Reading

References

Jun 1, 1990·Physiology & Behavior·C A HardyR Ader
Aug 1, 1988·Biological Psychiatry·P W Gold
Jan 1, 1987·Psychopharmacology·R G Lister
Sep 1, 1984·Psychosomatic Medicine·S E LockeR M Williams
Apr 23, 1982·Science·M A VisintainerM E Seligman
Mar 31, 1994·Behavioural Brain Research·P SimonJ Costentin
Dec 29, 1995·Annals of the New York Academy of Sciences·C SongB E Leonard
Feb 1, 1996·Endocrine Reviews·H O Besedovsky, A del Rey
Mar 24, 1998·Annual Review of Medicine·B R Zetter
May 6, 1999·Journal of Neuroimmunology·J de GrootJ M Koolhaas
May 25, 1999·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S O HoferH J Hoekstra
Mar 29, 2001·Physiology & Behavior·C de P PortelaJ Palermo-Neto
Mar 29, 2001·Nature Immunology·M J SmythJ A Trapani
Sep 22, 2001·Brain, Behavior, and Immunity·E P ZorrillaK Schmidt
Mar 22, 2002·Nature Reviews. Immunology·A Cerwenka, L L Lanier
Mar 5, 2003·Brain, Behavior, and Immunity·João Palermo-NetoWelker Robespierre de Souza
Oct 15, 2003·Neuroimmunomodulation·Maria Sílvia F A MorgulisJoão Palermo-Neto
Nov 6, 2003·Toxicology·Maritha Marcusson-Ståhl, Karin Cederbrant
Aug 12, 2005·Proceedings of the National Academy of Sciences of the United States of America·Gary R SmallBrian R Walker
Nov 3, 2005·Nature Clinical Practice. Oncology·Steven F Moss, Martin J Blaser

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Citations

Jan 25, 2011·Genes, Brain, and Behavior·W ItoA Morozov
Jul 9, 2008·Stress : the International Journal on the Biology of Stress·L R FrickG A Cremaschi
Mar 24, 2007·Frontiers in Neuroendocrinology·Alessandro Bartolomucci
Feb 25, 2009·Annals of the New York Academy of Sciences·Frederico Azevedo Costa-PintoJoao Palermo-Neto
Aug 29, 2012·The British Journal of Dermatology·E M J Peters
Jun 10, 2011·Medical Hypotheses·F EgydioM L Andersen
Apr 15, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Bobby Habig, Elizabeth A Archie
Sep 29, 2009·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·W M Quinteiro-FilhoJ Palermo-Neto
Dec 7, 2018·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Karen L Svenson, Beverly Paigen
Nov 19, 2019·Frontiers in Oncology·Claudia B Colon-EchevarriaGuillermo N Armaiz-Pena
Aug 11, 2015·Behavioural Pharmacology·Daniela Baptista-de-SouzaAzair Canto-de-Souza
Mar 15, 2018·Frontiers in Behavioral Neuroscience·Gráinne I McNamaraAnthony R Isles
Aug 24, 2007·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Glaucie Jussilane Alves, João Palermo-Neto
Apr 7, 2018·Frontiers in Behavioral Neuroscience·Aki TakahashiScott J Russo
Aug 7, 2021·Immunology and Cell Biology·Nicole N Scheff, Jami L Saloman

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