Variations in Patients' Perceptions and Use of Generic Drugs: Results of a National Survey

Journal of General Internal Medicine
Aaron S KesselheimEric G Campbell

Abstract

Over 84 % of all prescriptions in the US are filled as generic drugs, though in prior surveys, patients reported concerns about their quality. We aimed to survey patients' perceptions and use of generic drugs. Our survey (administered August 2014) assessed patients' skepticism about generic drug safety and effectiveness and how often they requested brand-name drugs. Chi-square tests and two-sample t-tests assessed associations between patient demographics and the outcomes. Our sample frame was the CVS Advisor Panel, a national database of 124,621 CVS customers. We randomly selected 1450 patients with self-reported chronic conditions who filled at least one prescription in the prior 3 months. We assessed how often patients reported asking their physicians to prescribe a brand-name over a generic drug in the last year, and "generic skepticism," defined as not believing generic drugs were as safe, effective, had the same side effects, and contained the same active ingredients as brand-name drugs. Of the 1,442 patients with valid addresses, 933 responded (65 % response rate) and 753 took the full survey. A vast majority (83 %) agreed that physicians should prescribe generic drugs when available, and 54 % said they had not asked the...Continue Reading

References

Apr 16, 1997·JAMA : the Journal of the American Medical Association·B J DongF S Greenspan
Oct 26, 2005·International Journal of Clinical Pharmacology and Therapeutics·W HimmelE Hummers-Pradier
Mar 6, 2008·JAMA : the Journal of the American Medical Association·Rebecca L WaberDan Ariely
Aug 19, 2008·Patient Education and Counseling·Alice IosifescuAlex D Federman
Dec 4, 2008·JAMA : the Journal of the American Medical Association·Aaron S KesselheimWilliam H Shrank
Mar 12, 2009·Health Affairs·William H ShrankNiteesh K Choudhry
May 16, 2009·Psychology, Health & Medicine·Maria J FigueirasRob Horne
Mar 26, 2011·The American Journal of Medicine·William H ShrankNiteesh K Choudhry
Apr 1, 2011·Pharmacotherapy·Francesco DentaliUNKNOWN Warfarin Associated Research Projects and Other Endeavors (WARPED) Consortium
May 3, 2012·JAMA : the Journal of the American Medical Association·Timothy P Johnson, Joseph S Wislar
Dec 12, 2012·The New England Journal of Medicine·Janet WoodcockLawrence X Yu
Sep 16, 2014·Annals of Internal Medicine·Joshua J GagneWilliam H Shrank
Jan 16, 2015·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Li-Ling HuangGera E Nagelhout
Feb 24, 2015·Social Science & Medicine·Niels Skipper, Rune Vejlin

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Citations

Apr 4, 2017·Pharmacoepidemiology and Drug Safety·Aaron S KesselheimEric G Campbell
Apr 27, 2017·Journal of Oncology Practice·Christopher T Chen, Aaron S Kesselheim
Nov 23, 2017·Clinical Pharmacology and Therapeutics·Ameet SarpatwariAaron S Kesselheim
Nov 12, 2018·Clinical Pharmacology and Therapeutics·Ameet SarpatwariAaron S Kesselheim
Dec 30, 2018·Clinical Pharmacology and Therapeutics·Joshua J GagneRishi J Desai
Jan 15, 2019·Therapeutic Innovation & Regulatory Science·Jodi B SegalRobert J Romanelli
May 10, 2020·Clinical Pharmacology and Therapeutics·Evan D KharaschEric J Lenze
Jan 26, 2017·Frontiers in Pharmacology·Mingming LiFeng Xu
Sep 30, 2020·Journal of General Internal Medicine·Ali ThaverVineet M Arora
Sep 13, 2017·The Milbank Quarterly·Olivier J WoutersMartin McKEE
Feb 28, 2018·Journal of Managed Care & Specialty Pharmacy·Ahmed U MishukRichard Hansen
Jan 12, 2019·Journal of General Internal Medicine·Ameet SarpatwariAaron S Kesselheim
Mar 3, 2021·JAMA Network Open·Mariana P SocalGerard F Anderson
Nov 22, 2020·Journal of the American Pharmacists Association : JAPhA·Natalie S HohmannJingjing Qian
Apr 9, 2021·Journal of Clinical Pharmacy and Therapeutics·Justine AlderferT Joseph Mattingly
Nov 25, 2021·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Bharati BhardwajaKari L Olson
Dec 10, 2021·Circulation. Cardiovascular Quality and Outcomes·Iris MaAlexander T Sandhu

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