Variations of lacrimal fluid peroxidase activity in female and male rats

Ophthalmic Research
F MadiaG Marcozzi

Abstract

Previous research from this laboratory showed that human lacrimal fluid peroxidase has cyclic variations during the menstrual cycle, correlated with plasma levels of 17beta-oestradiol. In the present investigation, variations of enzyme activity and total protein content during the oestrous cycle of young adult female rats are analysed. Effects from circadian rhythm and a gender-related influence are also examined. In female rats, as in women, lacrimal fluid peroxidase activity shows cyclic variations; in fact, it significantly (p < 0.05) changes during the different phases of the oestrous cycle. In contrast, in males such variations do not occur. Thus, we suggest that gender seems to exert a significant influence on the secretion of this specific tear protein, probably by a direct effect of oestrogens.

Citations

Jan 18, 2003·Autonomic Neuroscience : Basic & Clinical·Claudia Anesini, Enri Borda
Apr 27, 2005·Survey of Ophthalmology·P D GuptaA R Vasavada
Nov 25, 2020·Indian Journal of Ophthalmology·Deepak MishraPallak Kusumgar

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