Varicella, ephemeral breastfeeding and eczema as risk factors for multiple sclerosis in Mexicans

Acta Neurologica Scandinavica
R TarratsJulio Sotelo

Abstract

It has been suggested that the incidence of multiple sclerosis (MS) in Mexico and other countries of Latin America has increased steadily for the last two decades. We made a thorough search of antecedents on MS patients that could be potential risk factors. A case-control study was conducted using a questionnaire that included demographic, nutritional, infectious and personal antecedents previously identified in other reports as possible risk factors for MS. The frequency of varicella, ephemeral breastfeeding and eczema in the medical history of MS patients were significant when compared with controls; all appeared to be mutually additive. However, they were unrelated with clinical characteristics or disease severity. During the last decades, breastfeeding has been abandoned in large segments of society and the incidence of varicella and childhood eczema keeps a north-south gradient similar to that described for MS. These factors may participate in the sharp increase of MS in countries like Mexico traditionally considered as an area of very low incidence.

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Citations

Apr 3, 2007·Journal of Neurology·Julio SoteloBenjamin Pineda
Nov 19, 2011·Multiple Sclerosis International·Julio Sotelo, Teresa Corona
Oct 29, 2005·Neuroepidemiology·Teresa Corona, Gustavo C Román
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Mar 29, 2011·Neurologic Clinics·Sreeram V Ramagopalan, A Dessa Sadovnick
May 21, 2010·Clinical Neurology and Neurosurgery·Graciela OrdoñezJulio Sotelo
Oct 25, 2008·Clinical Neurology and Neurosurgery·Mayela Rodríguez-ViolanteTeresa Corona
Jul 31, 2007·Journal of the Neurological Sciences·Julio Sotelo
Nov 12, 2005·Acta Neurologica Scandinavica·C Perez-CesariJ Sotelo
Feb 29, 2008·Annals of Neurology·Julio SoteloBenjamin Pineda
Aug 29, 2006·Clinical Neurology and Neurosurgery·Jacqueline CordovaJulio Sotelo
Mar 14, 2014·Neurological Research·Guillermo Espinosa-RamírezJulio Sotelo
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Jan 13, 2015·Clinical Neurology and Neurosurgery·Graciela OrdoñezJulio Sotelo
Mar 19, 2014·Clinical Neurology and Neurosurgery·Julio SoteloJosé Flores
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