Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent adult

Open Forum Infectious Diseases
Ramachandiran NandhagopalDon Gilden

Abstract

Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

References

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Feb 27, 2010·Current Topics in Microbiology and Immunology·Don GildenMaria A Nagel

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Citations

Dec 21, 2018·BMJ Case Reports·Stéphane DaugerPeter Jones
Apr 3, 2016·The Journal of Infectious Diseases·Don GildenMaria A Nagel
Jul 6, 2018·MMW Fortschritte der Medizin·Igor-Wolfgang BlauGeorg Maschmeyer

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Methods Mentioned

BETA
biopsy

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