PMID: 9558014Apr 29, 1998Paper

Varied morphology of spontaneous single muscle fiber discharges

American Journal of Physical Medicine & Rehabilitation
D Dumitru, J C King

Abstract

Fibrillation potentials and positive sharp waves have rather stereotypical morphologies generally conforming to a triphasic initially positive and biphasic initially positive waveform, respectively. Careful attention during the needle electromyographic examination of muscle tissue with unstable resting membrane potentials, however, frequently reveals spontaneous potentials with appearances conforming to not only those described above but also waveforms with morphologies that can best be characterized as a blend of both a fibrillation potential and positive sharp wave. These "hybrid" or composite waveforms are hypothesized to arise from an electrical summation of two single muscle fibers repetitively discharging in a time-locked manner. Five individuals with lower motor neuron disorders displaying spontaneous discharges at rest during the needle electromyographic were examined. The spontaneous discharges were categorized according to their morphology. Stereotypical positive and negative onset fibrillation potentials and positive sharp waves from these patients were digitized. Computer simulations summating the digitized waveforms were successful in reproducing all of the observed "hybrid" waveforms documented in the patients. Th...Continue Reading

References

Mar 1, 1979·Neuropathology and Applied Neurobiology·D K DasturD K Manghani
Jan 1, 1980·Journal of the Neurological Sciences·A Sĭrca, M Susec-Michieli
Jan 1, 1997·Archives of Physical Medicine and Rehabilitation·K HachisukaH Ogata

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Citations

Jun 8, 2000·Muscle & Nerve·S D NandedkarE V Stalberg
Aug 3, 2000·Muscle & Nerve·D Dumitru, J C King
Mar 14, 2000·Neuromuscular Disorders : NMD·G L JiangY D Gu
Oct 6, 2000·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·D F StegemanK Roeleveld
Oct 19, 2013·American Journal of Public Health·Heather BeilJessica Y Lee

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