Jul 25, 2008

Vasa and nanos are coexpressed in somatic and germ line tissue from early embryonic cleavage stages through adulthood in the polychaete Capitella sp. I

Development Genes and Evolution
Kariena K Dill, Elaine C Seaver


Members of the vasa and nanos gene families are involved in germ line development in a number of diverse animals. As a polychaete annelid model for studies of the germ line, Capitella sp. I has several advantages including the presence of dedicated gonads, individuals that reproduce multiple times, and the presence of males, females, and hermaphrodites. Germ line development has not been characterized in Capitella sp. I, nor is the mechanism of germ line specification generally well understood in annelids. We have cloned vasa and nanos orthologues from Capitella sp. I and found that both CapI-vasa and CapI-nanos transcripts are expressed in developing gametes of sexually mature adults. Characterization of both these genes during embryonic, larval, and juveniles stages reveals expression in multiple somatic tissues for CapI-vasa and CapI-nanos with largely overlapping but not identical expression patterns. In early cleavage stages, both transcripts are broadly expressed; following gastrulation, expression is observed in the presumptive brain, mesodermal bands, and developing foregut. Using CapI-nanos and CapI-vasa as markers, we have identified putative primordial germ cells (PGCs) in larvae, which are initially present as small...Continue Reading

Mentioned in this Paper

Capitella teleta
Transcription, Genetic
Embryonic Cleavage
Cytokinesis of the Fertilized Ovum

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