Vascular calcification: it's all the RAGE!

Apr 8, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Hoa Ton KhaFarhad Parhami

Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis

Jul 23, 2005·Annals of the New York Academy of Sciences·William KimAnn Marie Schmidt

Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification

Mar 11, 2006·Circulation Research·Xianwu LiCecilia M Giachelli

Networks and hubs for the transcriptional control of osteoblastogenesis

Oct 20, 2006·Reviews in Endocrine & Metabolic Disorders·Jane B LianDaniel W Young

Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/- mice.

Oct 13, 2007·Arteriosclerosis, Thrombosis, and Vascular Biology·Ziyad Al-AlyDwight A Towler

Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.

Apr 2, 2008·The Journal of Biological Chemistry·Chang Hyun ByonYabing Chen

Vascular calcification: pathobiology of a multifaceted disease.

Jun 4, 2008·Circulation·Linda L Demer, Yin Tintut

Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans.

Aug 30, 2008·Journal of the American College of Cardiology·Jordan D MillerDonald D Heistad

Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis

Oct 8, 2008·Circulation·Rukshana C ShroffCatherine M Shanahan

Calcific aortic stenosis: lessons learned from experimental and clinical studies.

Nov 22, 2008·Arteriosclerosis, Thrombosis, and Vascular Biology·Nalini M Rajamannan

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate.

Dec 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Larry PedersonMerry Jo Oursler

Vascular calcification: the three-hit model

May 28, 2009·Journal of the American Society of Nephrology : JASN·Sharon M Moe

Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK

Jul 3, 2009·Journal of Vascular Research·Takahisa TanikawaYoshiya Tanaka

Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein.

Aug 8, 2009·Circulation Research·Yucheng YaoKristina I Boström

S100A12 mediates aortic wall remodeling and aortic aneurysm.

Oct 31, 2009·Circulation Research·Marion Hofmann BowmanElizabeth M McNally

Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.

Nov 3, 2009·Genesis : the Journal of Genetics and Development·Maria H FestingCecilia M Giachelli

S100 Calgranulins in inflammatory arthritis

Nov 26, 2009·Immunology and Cell Biology·Chandima PereraCarolyn L Geczy

Circulating soluble receptor for advanced glycation end-product levels are decreased in patients with calcific aortic valve stenosis

Jan 16, 2010·Atherosclerosis·Giuseppina BastaAnnamaria Mazzone

Inflammation and the osteogenic regulation of vascular calcification: a review and perspective.

Jan 27, 2010·Hypertension·Jian-Su ShaoDwight A Towler

The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature

Mar 20, 2010·Circulation Research·Shi Fang YanAnn Marie Schmidt

Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis.

May 22, 2010·Circulation Research·Su-Li ChengDwight A Towler

Regulatory mechanisms in vascular calcification.

Jul 29, 2010·Nature Reviews. Cardiology·Andrew P SageLinda L Demer

S100A12 in vascular smooth muscle accelerates vascular calcification in apolipoprotein E-null mice by activating an osteogenic gene regulatory program

Oct 23, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Marion A Hofmann BowmanElizabeth M McNally

Arterial calcification is driven by RAGE in Enpp1-/- mice

Nov 26, 2010·Journal of Vascular Research·Denise L Cecil, Robert A Terkeltaub

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Citations

High mobility group box 1 (HMGB1) mediates high-glucose-induced calcification in vascular smooth muscle cells of saphenous veins

Aug 10, 2013·Inflammation·Yongyi WangSong Xue

Calcific aortic valve stenosis: methods, models, and mechanisms.

May 28, 2011·Circulation Research·Jordan D MillerDonald D Heistad

Genetics in arterial calcification: pieces of a puzzle and cogs in a wheel.

Aug 20, 2011·Circulation Research·Frank RutschRobert Terkeltaub

Inverse association between circulating levels of soluble receptor for advanced glycation end-products and coronary plaque burden

Jul 13, 2012·Journal of Atherosclerosis and Thrombosis·Giuseppina BastaPaolo Marraccini

Nonenzymatic glycation interferes with fibronectin-integrin interactions in vascular smooth muscle cells.

Dec 23, 2016·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Srijita DharMichael A Hill

Functional role of soluble receptor for advanced glycation end products in stroke

Jan 5, 2013·Arteriosclerosis, Thrombosis, and Vascular Biology·Sung-Chun TangJiann-Shing Jeng

RANKL-OPG and RAGE modulation in vascular calcification and diabetes: novel targets for therapy

Aug 13, 2014·Diabetologia·Agbor NdipM Yvonne Alexander

Fibroblast growth factor signaling in the vasculature

Mar 31, 2015·Current Atherosclerosis Reports·Xuehui YangRobert Friesel

The molecular biology and pathophysiology of vascular calcification

Apr 2, 2014·Postgraduate Medicine·Mark F McCarty, James J DiNicolantonio

Circulating S100A12 Levels Are Associated with Progression of Abdominal Aortic Calcification in Hemodialysis Patients

Feb 26, 2016·PloS One·Byoung Ho ChoiJi Yong Jung

A novel role of cellular interactions in vascular calcification

May 4, 2017·Journal of Translational Medicine·Adham Sameer A BardeesiHui Huang

S100/RAGE-Mediated Inflammation and Modified Cholesterol Lipoproteins as Mediators of Osteoblastic Differentiation of Vascular Smooth Muscle Cells

Nov 24, 2018·Frontiers in Cardiovascular Medicine·Bijoy ChellanMarion A Hofmann Bowman

Increased phagocytic NADPH oxidase activity associates with coronary artery calcification in asymptomatic men

Apr 22, 2017·Free Radical Research·Oscar BeloquiGuillermo Zalba

Neuroprotection by the PARP inhibitor PJ34 modulates cerebral and circulating RAGE levels in rats exposed to focal brain ischemia

Dec 3, 2014·European Journal of Pharmacology·Rosaria GrecoDiana Amantea