Vascular response to modified Widman flap surgery in monkeys

Journal of Periodontology
R G CafffesseC E Nasjleti

Abstract

Revascularization of the periodontal tissues was studied after flap surgery. Modified Widman flap procedures were performed in four young Rhesus monkeys. All premolars and molars were involved. Experimental periods covered from 1 day to 90 days. The animals were sacrificed by exsanguination and perfused through the carotid arteries with a combined solution of equal parts of India ink and 10% buffered formalin solution. After fixation and decalcification, part of the blocks were processed to obtain cleared specimens following the Spalteholtz method. The remaining blocks were processed for routine histologic examination. The findings, mainly from the cleared specimens, showed that 1 day after surgery the supraperiosteal vessels in the flap demonstrated an overt hyperemic response. Patency of the vessels in the periodontal membrane and cancellous bone was evident; however, vessels were not depicted in the exposed cortical bone, nor in the clot. Vascular continuity apical to the surgical detachment was observed. In 3 to 4 days vascular proliferation within the organizing clot was observed and anastomosis between the gingiva and cancellous bone or periodontal membrane started to develop. At 7 days anastomoses were evident and vasodi...Continue Reading

References

Aug 1, 1974·Journal of Periodontology·S P Ramfjord, R R Nissle
Jul 1, 1968·Journal of Periodontology·R G CaffesseC E Nasjleti

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Citations

Nov 8, 2005·Head & Face Medicine·Johannes KleinheinzUlrich Joos
Dec 1, 1989·Journal of Periodontology·G M BowersE Romberg
Apr 24, 2007·Journal of Clinical Periodontology·M RetzepiN Donos
Apr 23, 2013·Clinical Oral Implants Research·Doğan KanerAnton Friedmann
Jun 4, 2015·Clinical Oral Implants Research·Farah Asa'adAldo B Giannì
May 16, 2003·Journal of Periodontology·Takahiro NobutoKazuyoshi Obayashi
Oct 13, 2006·Journal of Periodontology·Debby Hwang, Hom-Lay Wang

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