Vascularity as assessed by Doppler intraoral ultrasound around the invasion front of tongue cancer is a predictor of pathological grade of malignancy and cervical lymph node metastasis

Dento Maxillo Facial Radiology
Chika YamamotoKunihiro Miwa

Abstract

To quantitatively evaluate the relationship of vascularity of tongue cancer as demonstrated on intraoral ultrasonography images and tumour thickness with pathological grade of malignancy and the presence of cervical lymph node metastases. 18 patients with tongue cancer were enrolled in this retrospective study. Using Doppler ultrasonography images of the invasion front of the cancers along the length of their tumour boundaries, three vascular indexes were analysed quantitatively, namely ratio of blood flow signal area within the cancer to whole tumour area (BAR), blood flow signal number ratio (BNR) and blood flow signal width ratio (BWR). The associations between these three indexes and occurrence of cervical lymph node metastasis and pathological grade of malignancy [Yamamoto-Kohama (YK) classification] were assessed. Furthermore, the relationship between tumour thickness and occurrence of cervical lymph node metastasis was evaluated on B-mode intraoral ultrasonography images. There was no significant association between BAR and tumour thickness or occurrence of cervical lymph node metastasis. The BNRs and BWRs of patients with cervical lymph node metastasis were significantly higher than those of patients without nodal invol...Continue Reading

References

Feb 1, 1973·Acta Radiologica: Therapy, Physics, Biology·P A JakobssonB Mårtensson
Dec 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L M Ellis, I J Fidler
Jun 29, 2001·Head & Neck·M HelbigA J Tasman
Dec 24, 2003·International Journal of Oral and Maxillofacial Surgery·E J M Hannen, D Riediger
Apr 29, 2004·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Ronald SchimmingRainer Schmelzeisen
Jul 27, 2005·Journal of Cancer Research and Clinical Oncology·Panayiotis A KyzasNiki J Agnantis
Dec 17, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Ayano KaneoyaKen Omura
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Apr 15, 2014·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Yasuhisa ShinozakiNobuyuki Taniguchi

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