Vascularized iliac bone graft for iliosacral bone defect after tumor excision

Clinical Orthopaedics and Related Research
Jun NishidaTadashi Shimamura

Abstract

We present the clinical outcome of five patients who had reconstruction of large osseous defects in the iliosacral region after excision of aggressive bone tumors using pedicled-or free-vascularized iliac bone grafts. Surgical margin, incidence of recurrence and metastasis, patient survival, time to bone union, and postoperative function were evaluated. Limb-salvage surgery resulted in wide excisions in two patients with giant-cell tumors of bone and chordoma, respectively, a marginal excision in one patient with a schwannoma, and intralesional excisions to preserve nerve roots in two patients with giant-cell tumors. There was no recurrence at final followup in any of the patients. Bone union required an average of 5.4 months. The postoperative functional results were excellent in all patients except for the patient with a chordoma. In one of the patients with a giant-cell tumor, the screws and rod were removed partially because of skin necrosis in the instrumentation area. This technique is considered a good alternative for reconstruction of a large osseous defect in the pelvis because graft harvest is relatively simple and rapid, especially if a pedicled iliac bone transfer is performed.

References

Apr 1, 1978·Plastic and Reconstructive Surgery·G I Taylor, N Watson
Dec 1, 1979·Plastic and Reconstructive Surgery·G I TaylorR Corlett
Jan 1, 1984·The Journal of Bone and Joint Surgery. British Volume·P C Leung, Y Y Chow
Sep 12, 2000·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Y YoshidaH J Mankin
Dec 29, 2000·The Journal of Bone and Joint Surgery. British Volume·S NagoyaS Ishii
Jul 14, 2001·Clinical Orthopaedics and Related Research·F LanglaisH Thomazeau
Sep 10, 2002·Clinical Orthopaedics and Related Research·Eva SchwameisRainer Kotz
Mar 2, 2005·Clinical Orthopaedics and Related Research·Henry J MankinKevin A Raskin

❮ Previous
Next ❯

Citations

Jul 29, 2009·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Pieter H J BullensPieter Buma
Oct 8, 2009·Bioscience, Biotechnology, and Biochemistry·Shi-Wu DongJian-Sen Sun
Mar 30, 2012·Journal of Surgical Oncology·Ajay PuriS Laskar
Sep 20, 2012·Journal of Pediatric Orthopedics. Part B·Ajay PuriManish Pruthi
Jul 27, 2017·Der Orthopäde·U LenzeR von Eisenhart-Rothe
Jun 3, 2015·Orthopaedic Surgery·Kai ZhengXiu-chun Yu
Aug 28, 2020·Journal of Surgical Oncology·Sarah C TepperMatthew W Colman
Sep 10, 2021·Microsurgery·Stefano BastoniGiulio Menichini

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.