Vasculitic Neuropathies

Current Treatment Options in Neurology
Elie Naddaf, P J Dyck

Abstract

From pathological standpoint, we divide vasculitic neuropathies in two categories: nerve large arteriole vasculitides and nerve microvasculitis. It is also important to determine whether a large arteriole vasculitis has an infectious etiology as it entails different treatment approach. Treatment of non-infectious large arteriole vasculitides consists initially of induction therapy with corticosteroids. Adding an immunosuppressant, mainly cyclophosphamide, is often needed. Treatment of infectious large arteriole vasculitides needs a multidisciplinary approach to target both the underlying infection and the vasculitis. Corticosteroids are the first-line therapy for classic non-systemic vasculitic neuropathy. Stable or improving patients without biopsy evidence of active vasculitis can be either observed or treated. Currently, adding an immunosuppressant is only indicated for patients who continue to progress on corticosteroids alone or patients with a rapidly progressive course. The treatment of the radiculoplexus neuropathies such as diabetic lumbosacral radiculoplexus neuropathy, lumbosacral radiculoplexus neuropathy (in non-diabetic patients), and diabetic cervical radiculoplexus neuropathy, as well as painless diabetic motor ...Continue Reading

References

Feb 1, 1979·Seminars in Arthritis and Rheumatism·R L TraversG R Hughes
Mar 1, 1989·Neurology·S I MellgrenP J Dyck
May 1, 1988·Neurology·R J CaselliJ P Whisnant
Jan 1, 1989·Annals of the Rheumatic Diseases·C C ErhardtR N Maini
Aug 1, 1987·Brain : a Journal of Neurology·P J DyckP A Low
Jan 1, 1986·Neurology·J T KisselR C Griggs
Oct 1, 1981·Neurology·B A EvansP J Dyck
Apr 1, 1981·Neurology·J E Sander, F R Sharp
Nov 1, 1995·Archives of Neurology·D A KrendelL C Hopkins
Feb 1, 1994·Arthritis and Rheumatism·J C JennetteC G Kallenberg
May 1, 1994·Annals of Neurology·G SaidA Moulonguet
Oct 1, 1996·Brain : a Journal of Neurology·L DaviesJ G McLeod
Jun 1, 1997·QJM : Monthly Journal of the Association of Physicians·D AduP A Bacon
Dec 31, 1997·Mayo Clinic Proceedings·M K PascoeW J Litchy
Jun 13, 2000·Journal of Neuropathology and Experimental Neurology·P J DyckP J Dyck
Jun 30, 2000·QJM : Monthly Journal of the Association of Physicians·D R JayneC M Lockwood
Aug 31, 2001·Archives of Neurology·K de GrootE Reinhold-Keller
Aug 22, 2001·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P J DyckP J Dyck
Aug 8, 2002·Archives of Neurology·Michael P Collins, M Isabel Periquet
Jul 4, 2003·The New England Journal of Medicine·David JayneUNKNOWN European Vasculitis Study Group
Aug 9, 2003·Arthritis and Rheumatism·John H Stone, UNKNOWN Wegener's Granulomatosis Etanercept Trial Research Group
Sep 10, 2003·Neurology·M P CollinsJ T Kissel
Feb 6, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Naomi TsurikisawaKazuo Akiyama
Apr 29, 2005·Best Practice & Research. Clinical Rheumatology·Assil Saleh, John H Stone
Aug 30, 2005·Annals of the New York Academy of Sciences·Yair LevyYehuda Shoenfeld
Nov 3, 2005·Annals of Internal Medicine·Régis Sablé-FourtassouUNKNOWN French Vasculitis Study Group
Feb 9, 2006·Current Treatment Options in Neurology·Kenneth C Gorson
Apr 27, 2007·Allergology International : Official Journal of the Japanese Society of Allergology·Loïc Guillevin, Christian Pagnoux
May 24, 2007·Rheumatology·C MetzlerUNKNOWN German Network of Rheumatic Diseases
Apr 17, 2008·Annals of the Rheumatic Diseases·C MukhtyarUNKNOWN European Vasculitis Study Group

❮ Previous
Next ❯

Citations

Jul 1, 2016·American Journal of Physical Medicine & Rehabilitation·Fatemeh GhazaeiGholam Reza Raissi
Nov 22, 2018·Current Opinion in Rheumatology·Jonathan Graf, John Imboden
Jul 1, 2020·Terapevticheskiĭ arkhiv·I Y Golovach, Y D Yehudina
May 4, 2021·Frontiers in Pharmacology·Delia TulbăCristian Băicuș

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neurología : publicación oficial de la Sociedad Española de Neurología
J Pascual Calvet
PM & R : the Journal of Injury, Function, and Rehabilitation
Michael Jaffe, Richard Kendell
Revista de neurologia
A González-HernándezF Cabrera-Naranjo
Current Treatment Options in Neurology
Kenneth C Gorson
© 2021 Meta ULC. All rights reserved