Vasculitic neuropathy associated with minocycline use

Journal of Clinical Neuromuscular Disease
Pariwat ThaisetthawatkulPeter J Dyck

Abstract

Minocycline is an antibiotic used for the treatment of acne. It has been associated with several autoimmune syndromes, including drug-induced lupus, autoimmune hepatitis, and vasculitis. We report a case of a 28-year-old previously healthy woman who developed a left sciatic mononeuropathy 2 weeks after starting minocycline for acne. Magnetic resonance imaging studies supported the localization. A biopsy of the left sural nerve revealed acute nerve large arteriole necrotizing vasculitis. Her condition improved after the withdrawal of minocycline and a course of treatment with methylprednisolone. This case provides further evidence that minocycline may induce a nonsystemic necrotizing vasculitis.

References

Oct 1, 1996·Annals of the Rheumatic Diseases·O ElkayamD Caspi
Jul 16, 1999·Seminars in Arthritis and Rheumatism·O ElkayamD Caspi
Nov 11, 1999·Current Opinion in Pediatrics·A H Eichenfield
Apr 4, 2001·Rheumatology·T M LawsonB D Williams
Jan 31, 2002·The Annals of Pharmacotherapy·Sandra M ten HolderRonald J Falk
Jun 4, 2005·Arthritis and Rheumatism·Brent CulverKen Pischel
Jun 7, 2007·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Rodney TehraniDavid Eilers

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Citations

Oct 31, 2013·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Jun NakamuraMitsuhiro Nokubi
Mar 1, 2013·Muscle & Nerve·Georgios ManousakisAlan Pestronk
Nov 26, 2015·Neurology. Neuroimmunology and Neuroinflammation·John M BarattaChafic Karam
Apr 2, 2015·Therapeutic Advances in Musculoskeletal Disease·Franz Blaes
Oct 28, 2015·Current Rheumatology Reports·Rafael G Grau

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