Vasculopathy of large vessels in systemic sclerosis

Medicina clínica
Beatriz Tejera Segura, Iván Ferraz-Amaro

Abstract

Vasculopathy in systemic sclerosis is a severe, in many cases irreversible, manifestation that can lead to amputation. While the classical clinical manifestations of the disease have to do with the involvement of microcirculation, proximal vessels of upper and lower limbs can also be affected. This involvement of large vessels may be related to systemic sclerosis, vasculitis or atherosclerotic, and the differential diagnosis is not easy. To conduct a proper and early diagnosis, it is essential to start prompt appropriate treatment. In this review, we examine the involvement of large vessels in scleroderma, an understudied manifestation with important prognostic and therapeutic implications.

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Citations

Jan 3, 2016·Medicina clínica·Gabriel Horta-BaasMaria Del Socorro Romero-Figueroa

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