Vasculoplacental complications in pregnant women with HIV infection: a case-control study

American Journal of Obstetrics and Gynecology
Geoffroy CanlorbeElie Azria

Abstract

Data from the international literature suggest that there may be an association between maternal human immunodeficiency virus (HIV) infection and vasculoplacental complications during pregnancy. Studies on this subject have reached discordant conclusions. The aim of this study was to assess the incidence of vasculoplacental complications during pregnancy in women with and without HIV infection. This single-center case-control study compared the incidence of pregnancy-related hypertension, preeclampsia, eclampsia, and vascular intrauterine growth restriction in 280 women with HIV and 560 women not infected with HIV, matched for age, parity, and geographic origin. The incidence rates of pregnancy-related hypertension, preeclampsia, eclampsia, and vascular growth restriction did not differ between the women with and without HIV infection. The overall incidence of vasculoplacental complications did not differ between the 2 groups (7.5% vs 9.8%, respectively; P = .27). The risk of these was not associated with exposure to antiretroviral treatments, viral load, or CD4 T-cell counts at the beginning of pregnancy. This study shows no difference in the incidence of vasculoplacental complications between women with and without HIV infect...Continue Reading

References

Sep 1, 1996·Obstetrics and Gynecology·F D JohnstoneB A Hamilton
Aug 1, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J KurmanaviciusA Huch
Feb 13, 1999·American Journal of Obstetrics and Gynecology·C W RedmanI L Sargent
Aug 16, 2001·Proceedings of the National Academy of Sciences of the United States of America·A D SchecterM B Taubman
Oct 22, 2002·Lancet·R C WimalasunderaG P Taylor
Apr 5, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M R de GrootG Joubert
Aug 5, 2004·Obstetrics and Gynecology·K A FrankR C Schackis
Nov 16, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Rosiane MattarSilvia Daher
May 11, 2006·Journal of Clinical Nursing·Candice BodkinGayle Langley
Jun 15, 2007·Journal of Reproductive Immunology·David R Hall
Nov 4, 2008·HIV Clinical Trials·Marco FloridiaUNKNOWN Italian Group on Surveillance on Antiretroviral Treatment in Pregnancy
May 5, 2009·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Jelmer R PrinsJan Jaap H M Erwich
May 9, 2009·AIDS·Nelly BriandUNKNOWN ANRS French Perinatal Cohort
Nov 26, 2009·Current HIV Research·Jelena IvanovicUNKNOWN Pregnancy And Newborn Clinical Outcome Group in HIV Infection (PANCOH)
Mar 4, 2010·The Journal of Infectious Diseases·Kunjal PatelUNKNOWN P1025 team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Mar 5, 2010·American Journal of Perinatology·Sara N IqbalAhmet Alexander Baschat
Aug 24, 2010·HIV Medicine·C RudinUNKNOWN Swiss Mother & Child HIV Cohort Study (MoCHiV)
Dec 2, 2010·São Paulo Medical Journal = Revista Paulista De Medicina
Mar 31, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jeanne SibiudeLaurent Mandelbrot
Jun 28, 2014·Gynécologie, obstétrique & fertilité·L MandelbrotP Morlat

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