Vasoactive Inotropic Score as a Predictor of Mortality in Adult Patients With Cardiogenic Shock: Medical Therapy Versus ECMO

Revista Española De Cardiología
Soo Jin NaJeong Hoon Yang

Abstract

This study investigated whether the vasoactive inotropic score (VIS) is independently predictive of mortality in cardiogenic shock (CS). This study was retrospective, observational study. Patients who were admitted to the cardiac intensive care unit from January 2012 to December 2015 were screened, and 493 CS patients were finally enrolled. To quantify pharmacologic support, the patients were divided into 5 groups based on a quintile of VIS: 1 to 10, 11 to 20, 21 to 38, 39 to 85, and > 85. The primary outcome was in-hospital mortality. In-hospital mortalities in the 5 VIS groups in increasing order were 8.2%, 14.1%, 21.1%, 32.0%, and 65.7%, respectively (P < .001). Multivariable analysis indicated that VIS ranges of 39 to 85 (aOR, 3.85; 95%CI, 1.60-9.22; P = .003) and over 85 (aOR, 10.83; 95%CI, 4.43-26.43; P < .001) remained significant prognostic predictors for in-hospital mortality. With multiple logistic regression to remove any confounding effects, we found that the localized regression lines regarding the odds of death intersected each other's (medical therapy alone and combined extracorporeal membrane oxygenation group) path at VIS = 130. In contrast to linear correlation between VIS and mortality for patients treated wi...Continue Reading

Citations

Jan 19, 2019·The International Journal of Artificial Organs·Edis LjajikjMichiel Morshuis
Aug 12, 2021·Critical Care : the Official Journal of the Critical Care Forum·Pietro Di SantoUNKNOWN CAPITAL DOREMI investigators
Nov 12, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Junho HyunMin-Seok Kim
Dec 17, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Keita Saku, Jun Nakata

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