Vasoactive intestinal peptide interacts with alpha-adrenergic-, cholinergic-, and substance-P-mediated responses in rat parotid and submandibular glands.

Journal of Dental Research
E Bobyock, W S Chernick

Abstract

Secretory dose-response curves were obtained with both acetylcholine and phenylephrine treatment in rat parotid and submandibular glands. Vasoactive intestinal peptide (VIP), which produced relatively low volumes of protein-rich saliva in rat salivary glands, also enhanced acetylcholine-, phenylephrine-, and substance-P-mediated fluid and protein secretion when administered in combination with these agents. The specific mechanisms involved in the synergistic actions of VIP with substances such as acetylcholine, phenylephrine, and substance P, which are primarily linked to the production of fluid secretion in rat salivary glands, have yet to be determined.

References

Dec 1, 1986·Journal of Dental Research·E BobyockW S Chernick
Feb 1, 1987·Journal of Dental Research·J Ekström
Dec 1, 1987·The American Journal of Physiology·C DreuxB Rossignol
Jan 1, 1988·The American Journal of Physiology·P A Negulescu, T E Machen
Aug 1, 1988·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·J H Exton
Jan 1, 1989·Journal of Dental Research·W ChernickP Bradford
Jan 1, 1989·Trends in Pharmacological Sciences·T J Hallam, T J Rink
Feb 1, 1987·Journal of Dental Research·N Emmelin
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J M LundbergV Mutt

❮ Previous
Next ❯

Citations

May 1, 1992·Brain Research. Brain Research Reviews·C NilssonC Owman
Aug 20, 1996·Brain Research. Developmental Brain Research·T KusakabeH Sawada
Oct 24, 2003·Cell Calcium·Jason I E BruceDavid I Yule
Jan 1, 1997·Pharmacology & Therapeutics·P Holzer, U Holzer-Petsche
Jan 29, 1997·Regulatory Peptides·U HöckerfeltS Forsgren
Mar 20, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·L C AndersonG B Proctor
Feb 16, 2005·Annual Review of Physiology·James E MelvinTed Begenisich
Apr 17, 2013·International Journal of Peptides·Yosuke SuzukiMasaharu Takeyama
Dec 15, 2015·Periodontology 2000·Gordon B Proctor
Dec 13, 2006·Autonomic Neuroscience : Basic & Clinical·Gordon B Proctor, Guy H Carpenter
Sep 1, 1991·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·C NilssonC Owman
Jul 21, 2004·The Journal of Biological Chemistry·David A BrownDavid I Yule
Jan 12, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Takahide ShintaniYoshiki Shiba
Apr 26, 2020·The Journal of Pharmacology and Experimental Therapeutics·Hiroya MizutaniEiji Sasaki
Jun 7, 2006·Nihon yakurigaku zasshi. Folia pharmacologica Japonica·Akihiko Tanimura, Yosuke Tojyo
Jan 1, 1992·Acta Oto-laryngologica·C Hauser-KronbergerG W Hacker
Oct 9, 2002·The Journal of Biological Chemistry·Jason I E BruceTrevor J Shuttleworth

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.