Vasodilator Stress CMR and All-Cause Mortality in Stable Ischemic Heart Disease: A Large Retrospective Registry.

JACC. Cardiovascular Imaging
Victor Marcos-GarcesVicente Bodi

Abstract

This study explored the association of ischemic burden, as measured by vasodilator stress cardiovascular magnetic resonance (CMR), with all-cause mortality and the effect of revascularization on all-cause mortality in patients with stable ischemic heart disease (SIHD). In patients with SIHD, the association of ischemic burden, derived from vasodilator stress CMR, with all-cause mortality and its role for decision-making is unclear. The registry consisted of 6,389 consecutive patients (mean age: 65 ± 12 years; 38% women) who underwent vasodilator stress CMR for known or suspected SIHD. The ischemic burden (at stress first-pass perfusion imaging) was computed (17-segment model). The effect of CMR-related revascularization (within the following 3 months) on all-cause mortality was retrospectively explored using the electronic regional health system registry. During a 5.75-year median follow-up, 717 (11%) deaths were documented. In multivariable analyses, more extensive ischemic burden (per 1-segment increase) was independently related to all-cause mortality (hazard ratio: 1.04; 95% confidence interval: 1.02 to 1.07; p < 0.001). In 1,032 1:1 matched patients using a limited number of variables (516 revascularized, 516 non-revascula...Continue Reading

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Citations

Feb 11, 2021·Journal of Clinical Medicine·Ana Gabaldon-PerezVicente Bodi
May 11, 2021·European Journal of Preventive Cardiology·Julio NúñezVicent Bodí
Jun 25, 2021·Frontiers in Cardiovascular Medicine·Théo PezelOtávio R Coelho-Filho
Nov 6, 2021·European Journal of Preventive Cardiology·Christos P Kotanidis, Chrysovalantou Nikolaidou

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