Vasomotor reactivity is similarly impaired in patients with Alzheimer's disease and patients with amyloid hemorrhage

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Manuel Menendez-GonzalezRenee Ribacoba

Abstract

Cerebral amyloid angiopathy (CAA) might alter cerebral hemodynamics. Impairment of vasomotor reactivity may constitute a biomarker of amyloid angiopathy and therefore it may be useful to distinguish disorders with CAA from other conditions. The aim of this study was to assess the vasomotor reactivity in two conditions characterized by CAA: Alzheimer's disease and amyloid hemorrhage. We assessed the vasomotor using transcranial Doppler and the breath-holding method. Responses obtained in controls were higher than in patients with Alzheimer's or with antecedent of amyloid hemorrhage while there was no statistical difference in the comparison between these last two groups. The vasomotor reactivity seems to be similarly impaired in Alzheimer's disease and amyloid hemorrhage patients.

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Citations

Jul 24, 2012·Dementia and Geriatric Cognitive Disorders Extra·Hannah A D KeageScott Elliott
Apr 25, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·YongSoo ShimDong-Won Yang
Feb 28, 2015·Journal of Alzheimer's Disease : JAD·Luigi Yuri Di MarcoAlejandro F Frangi
Oct 25, 2016·Neurologia i neurochirurgia polska·Łukasz Smoliński, Anna Członkowska
Aug 4, 2016·Ageing Research Reviews·Ken NagataYuichi Sato
Feb 13, 2019·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Mohammed AlwatbanGreg Bashford
Mar 23, 2018·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Mohammed AlwatbanGregory R Bashford
Apr 5, 2018·Journal of Alzheimer's Disease : JAD·Barbora Soukupova UrbanovaAles Tomek

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