Vasomotor symptoms in menopause: where we've been and where we're going

Journal of Women's Health
JoAnn V Pinkerton, Adrienne S Zion

Abstract

The decline in gonadal hormones during menopause gives rise to a wide range of physiological and psychological changes with the potential to significantly impact a woman's health and quality of life. Most notable among these are menopausal vasomotor symptoms, hot flushes and night sweats, along with mood and sleep disturbances. Given the biological and social significance of menopause, it is remarkable that the language used to describe this event and its associated symptoms is inconsistent. This review traces the history of Western medical writing about menopause-associated vasomotor symptoms and considers how terminology has contributed to the current confusion regarding symptoms and symptom reporting. Although hormone therapy is the only treatment for menopausal symptoms currently approved by the U.S. Food and Drug Administration, other forms of therapy are under evaluation. Agreement about the definition of menopause and its associated symptoms is critically important for the design and evaluation of new therapies and for the optimal treatment of women during this important phase of their lives.

References

Jan 1, 1990·Annals of the New York Academy of Sciences·F Kronenberg
Jul 1, 1997·The American Journal of Medicine·W A GhaliM A Moskowitz
Jun 27, 1998·Maturitas·J G Greene
Aug 8, 1998·Fertility and Sterility·R R Freedman
Mar 17, 1999·American Journal of Obstetrics and Gynecology·G A Bachmann
Jul 20, 1999·American Journal of Obstetrics and Gynecology·R R Freedman, W Krell
Feb 25, 2000·Maturitas·J E BlumelA Sanjuan
Jul 21, 2000·Aging : Clinical and Experimental Research·M F Sowers
Aug 29, 2000·Obstetrics and Gynecology·L DennersteinH G Burger
Nov 7, 2000·Maturitas·H H Berendsen
May 2, 2001·Social Science & Medicine·N E AvisM Kagawa-Singer
Nov 28, 2001·Menopause : the Journal of the North American Menopause Society·W H Utian
May 7, 2002·American Journal of Respiratory and Critical Care Medicine·Terry YoungDaniel J Gottlieb
Nov 20, 2002·Menopause : the Journal of the North American Menopause Society·Wulf H UtianJames C Hamilton
Dec 14, 2002·Lancet·Vered StearnsDanielF Hayes
Feb 11, 1965·The New England Journal of Medicine·R B GREENBLATT
Jan 13, 2004·Menopause : the Journal of the North American Menopause Society·UNKNOWN North American Menopause Society
May 29, 2004·Menopause : the Journal of the North American Menopause Society·Lisa A BoothbySimon Kipersztok
Oct 2, 2004·Obstetrics and Gynecology·Erin E KrebsTimothy J Wilt
Oct 2, 2004·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists Women's Health Care Physicians
Nov 24, 2004·Sleep Medicine Reviews·Karen E Moe
Dec 14, 2004·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Phyllis Kernoff MansfieldPatricia Bartholow Koch
Jan 26, 2005·The Journal of the British Menopause Society·Päivi Polo-Kantola, Risto Erkkola
May 11, 2005·Expert Opinion on Investigational Drugs·Darlene C Deecher
Jul 15, 2005·JAMA : the Journal of the American Medical Association·Judith K OckeneJennifer Hays

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Citations

Mar 9, 2013·Journal of Religion and Health·Filipa PimentaIsabel Leal
Sep 21, 2012·Climacteric : the Journal of the International Menopause Society·O K DuffyP C Hannaford
Sep 20, 2011·The Journal of the Association of Nurses in AIDS Care : JANAC·Sara E Dolan Looby
Jun 7, 2011·Annals of Medicine·Riitta LuotoClas-Håkan Nygård
Jul 29, 2009·Fertility and Sterility·David F ArcherJames H Pickar
May 8, 2009·Menopause : the Journal of the North American Menopause Society·Johan SvartbergElizabeth Barrett-Connor
Dec 17, 2008·Nature Clinical Practice. Endocrinology & Metabolism·David F Archer
Apr 17, 2014·Menopause : the Journal of the North American Menopause Society·Erin S LeBlancMarcia L Stefanick
Jun 6, 2019·Menopause : the Journal of the North American Menopause Society·Janet S CarpenterMark D Kesling
Feb 16, 2012·Menopause : the Journal of the North American Menopause Society·Jaana M MoilanenRiitta M Luoto
Jun 6, 2019·Menopause : the Journal of the North American Menopause Society·Janet S CarpenterKaren K Schmidt
Aug 28, 2019·Menopause : the Journal of the North American Menopause Society·Janet S CarpenterKaren K Schmidt
Aug 28, 2019·Menopause : the Journal of the North American Menopause Society·Janet S CarpenterMark D Kesling
Jul 16, 2019·Archives of Gynecology and Obstetrics·Cristina LarroyI Fernández Arias
Jun 24, 2017·Menopause : the Journal of the North American Menopause Society·Mônia Steigleder BianchiMaria Celeste Osório Wender

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