PMID: 37701Jan 1, 1979

Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents

Acta Medica Scandinavica. Supplementum
K EliassonK Sundqvist

Abstract

Twenty-one patients developed Raynaud's phenomenon during treatment with beta-adrenoceptor blocking agents. The vasospastic symptoms were obviously related to the treatment, but their pathogenesis is still controversial. A decrease in cardiac output might explain the phenomenon. According to our very preliminary data an alpha-adrenergic dominance caused by a direct effect on the peripheral circulation seems more probable. Vasospastic symptoms may arise after treatment with both cardioselective and non-selective beta blocking agents. Cautious prescription of beta blocking drugs to patients with preexisting peripheral vascular disease is recommended.

References

Jan 1, 1976·Acta Medica Scandinavica·L HanssonN C Henningsen
May 8, 1976·British Medical Journal·J C RodgerW R Livingstone
Jun 19, 1976·British Medical Journal·A J MarshallD W Barritt
Apr 16, 1977·British Medical Journal·C L van HerwaardenA van t'Laar
Sep 1, 1975·Progress in Cardiovascular Diseases·J D Coffman, W T Davies
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Jul 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·S JuliusR London
Jul 1, 1974·The Journal of Physiology·B EklundE Knutsson
Jul 29, 1971·The New England Journal of Medicine·J D Coffman, A S Cohen
Jan 4, 1969·British Medical Journal·B N Prichard, P M Gillam

Citations

Related Concepts

Adrenergic beta-Antagonists
Alprenolol Hydrochloride
Blood Circulation
Cardiac Output
Hypertensive Disease
Betalok
Rexigen
Raynaud Phenomenon
Timoptol

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