Vast Differences in Strain-Level Diversity in the Gut Microbiota of Two Closely Related Honey Bee Species.

Current Biology : CB
Kirsten M EllegaardPhilipp Engel

Abstract

Most bacterial species encompass strains with vastly different gene content. Strain diversity in microbial communities is therefore considered to be of functional importance. Yet little is known about the extent to which related microbial communities differ in diversity at this level and which underlying mechanisms may constrain and maintain strain-level diversity. Here, we used shotgun metagenomics to characterize and compare the gut microbiota of two honey bee species, Apis mellifera and Apis cerana, which diverged about 6 mya. Although the host species are colonized largely by the same bacterial 16S rRNA phylotypes, we find that their communities are host specific when analyzed with genomic resolution. Moreover, despite their similar ecology, A. mellifera displayed a much higher diversity of strains and functional gene content in the microbiota compared to A. cerana, both per colony and per individual bee. In particular, the gene repertoire for polysaccharide degradation was massively expanded in the microbiota of A. mellifera relative to A. cerana. Bee management practices, divergent ecological adaptation, or habitat size may have contributed to the observed differences in microbiota genomic diversity of these key pollinato...Continue Reading

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Citations

Jun 25, 2020·Nature Reviews. Microbiology·Andrea Du Toit
Oct 14, 2020·Environmental Microbiology Reports·Edward Ruby
Feb 11, 2021·Proceedings. Biological Sciences·Tobin J HammerNancy A Moran
Mar 7, 2021·Trends in Microbiology·Nancy ObengHinrich Schulenburg
Jul 18, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jay T OsvaticBenedict Yuen
Sep 21, 2021·Frontiers in Microbiology·Ana Cuesta-MatéMichael Poulsen
Feb 3, 2022·FEMS Microbiology Reviews·Michelle Z HotchkissJessica R K Forrest

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Datasets Mentioned

BETA
PRJNA598094

Methods Mentioned

BETA
amplicon sequencing
PCR
dissection

Software Mentioned

eggnog
vcflib
GNU parallel
hmmsearch
SPAdes
QuantStudio Design & Analysis
Picard
dbCAN2
mafft
- mapper

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