PMID: 9425810Jan 13, 1998Paper

Vector-host-parasite inter-relationships in leishmaniasis. II. Influence of blood meal from natural vertebrate hosts with and without Leishmania infantum and L. major on the proteolytic activity in the gut of Phlebotomus langeroni (Diptera: Psychodidae)

Journal of the Egyptian Society of Parasitology
S DabaBahira M El Sawaf

Abstract

Proteolytic activity in the gut of Phlebotomus langeroni (Nitzulescu) was studied at four subsequent 24 hours intervals post feeding on human, dog (Canis familiaris), rat (Rattus rattus) and turkey (Melagris gallopava) bloods with and without Leishmania infantum or L. major promastigotes. The gut proteolytic activity increased gradually after feeding to reach a maximum at 48 hours post feeding on any of the 12 studied blood meals. In all cases, the activity declined after 48 hours and almost terminated by 96 hours. In case of normal bloods, the proteolytic activity, at 48 hours post feeding, was the highest in case of dog followed by human, rat and turkey respectively. At this time interval the activity was relatively lower in case of human and dog blood mixed with L. infantum promastigotes than in their respective normal blood. The reverse was true in all other blood meal combinations. Promastigotes were alive and active in fresh gut smears of P. langeroni fed on human, dog and rat bloods mixed with either L. infantum or L. major, throughout the digestion period (1-4 days). They were arrested in P. langeroni within the first day post feeding on turkey blood mixed with either Leishmania species. The results of the present study...Continue Reading

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