Vegetable lipid sources affect in vitro biosynthesis of triacylglycerols and phospholipids in the intestine of sea bream (Sparus aurata)

The British Journal of Nutrition
María José CaballeroM S Izquierdo

Abstract

Despite the good growth performance of several fish species when dietary fish oil is partly replaced by vegetable oils, recent studies have reported several types of intestinal morphological alterations in cultured fish fed high contents of vegetable lipid sources. However, the physiological process implied in these morphological changes have not been clarified yet, since alterations in the physiological mechanisms involved in the different processes of lipid absorption could be responsible for such gut morphological features. The objective of the present study was to investigate the activities of reacylation pathways in fish, the glycerol-3-phosphate and the monoacylglycerol pathways, in order to clarify the intestinal triacylglycerol (TAG) and phospholipid biosynthesis to better understand the morphological alterations observed in the intestine of fish fed vegetable oils. Intestinal microsomes of sea bream fed different lipid sources (fish, soyabean and rapeseed oils) at three different inclusion levels were isolated and incubated with L-[(14)C(U)]glycerol-3-phosphate and [1-(14)C]palmitoyl CoA. The results showed that in this fish species the glycerol-3-phosphate pathway is mainly involved in phospholipid synthesis, whereas ...Continue Reading

References

May 1, 1992·The Biochemical Journal·H K StalsP E Declercq
Oct 18, 1996·The Journal of Biological Chemistry·G M Hatch, G McClarty
Aug 15, 2000·Annual Review of Nutrition·R A ColemanD M Muoio

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Citations

Nov 10, 2006·The British Journal of Nutrition·Maria José CaballeroMarisol Izquierdo
Jan 27, 2009·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Inge GeurdenKristina S Sundell

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