VenaSeal closure despite allergic reaction to n -butyl cyanoacrylate

Journal of Vascular Surgery Cases and Innovative Techniques
Leslie FiengoStephen Black

Abstract

The VenaSeal closure system (Medtronic, Minneapolis, Minn) is a nonthermal, minimally invasive method for the treatment of superficial venous insufficiency using a proprietary n-butyl cyanoacrylate. We report the case of a 45-year-old woman who underwent right great saphenous vein closure with VenaSeal and subsequently had a biphasic reaction to n-butyl cyanoacrylate, confirmed on patch testing that had negative results for other cyanoacrylates. Despite the initial allergic response, which settled with antihistamines, follow-up duplex ultrasound imaging confirmed successful great saphenous vein closure, and the affected vein remained in situ without further complication.

References

Jan 1, 1997·Archives of Surgery·N LabropoulosA N Nicolaides
Oct 9, 2012·Contact Dermatitis·Sangeetha Shanmugam, Mark Wilkinson
Apr 1, 2013·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Jose I AlmeidaThomas M Proebstle
Jan 1, 2015·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Thomas Michael ProebstleAlun Davies
Apr 20, 2018·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Daniele BissaccoMarco Piercarlo Viani
Aug 24, 2019·Journal of Vascular Surgery Cases and Innovative Techniques·Andrew D JonesAdam N Williams
Nov 2, 2019·Contact Dermatitis·Francisco J Navarro-TriviñoRicardo Ruiz-Villaverde

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