Venetoclax Adds a New Arrow Targeting Relapsed CLL to the Quiver

Cancer Cell
Kerry A Rogers, John C Byrd

Abstract

Inhibitors of B cell receptor signaling substantially changed the treatment of chronic lymphocytic leukemia as the first targeted agents to enter routine clinical practice. A recent paper by Roberts and colleagues describes an additional therapeutic target by reporting encouraging clinical results with venetoclax, an inhibitor of the antiapoptotic protein BCL2.

Citations

Jun 6, 2019·Chemical Society Reviews·Wei SangXiaoyuan Chen

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