Venous Thromboembolism After Surgical Treatment of Breast Cancer

Annals of Plastic Surgery
Arash Momeni, Justin P Fox

Abstract

Venous thromboembolism (VTE) remains a serious complication after the surgical treatment of breast cancer. Contemporary guidelines limit VTE chemoprophylaxis to the period of hospitalization. We conducted this study to evaluate the frequency of postdischarge VTE among surgically treated breast cancer patients and identify patient level factors associated with postdischarge VTE. Using Arkansas, Florida, Nebraska, and New York state inpatient databases, we conducted a retrospective cohort study of adult women who underwent surgical treatment for breast cancer between October 1, 2008, and September 30, 2013. The primary outcome was a VTE event within 90 days of discharge. Multivariable logistic regression modeling was used to identify patient factors associated with VTE development. The final sample included 52,547 women with most undergoing mastectomy without reconstruction (n = 25,665), followed by mastectomy with implant based reconstruction (n = 16,851), lumpectomy (n = 5319), and mastectomy with autologous reconstruction (n = 4622). There were 395 patients (0.8%) who developed at least 1 VTE. Of the 395 VTEs, 32.9% (n = 130) were identified before discharge, whereas 67.1% were identified within 90 days after discharge. Patien...Continue Reading

References

Oct 1, 1991·Seminars in Thrombosis and Hemostasis·J I ArcelusC I Traverso
Jul 1, 1994·Medical Care·L I IezzoniG A Coffman
Feb 7, 1998·Medical Care·A ElixhauserR M Coffey
Mar 29, 2002·The New England Journal of Medicine·David BergqvistUNKNOWN ENOXACAN II Investigators
Jun 20, 2003·Circulation·Clive Kearon
Dec 16, 2004·Circulation·Giancarlo Agnelli
Mar 11, 2005·The New England Journal of Medicine·Nils KucherSamuel Z Goldhaber
May 19, 2005·Disease-a-month : DM·Joseph A Caprini
Sep 8, 2005·The Journal of Urology·Joseph A Smith
Dec 5, 2009·BMJ : British Medical Journal·Siân SweetlandUNKNOWN Million Women Study collaborators
Nov 26, 2010·Journal of the American College of Surgeons·Christopher J PannucciEdwin G Wilkins
Oct 28, 2011·Plastic and Reconstructive Surgery·Christopher J PannucciEdwin G Wilkins
Jun 30, 2012·Plastic and Reconstructive Surgery·Robert X MurphyEdwin Wilkins
May 30, 2013·Plastic and Reconstructive Surgery·Morteza EnajatMarc A M Mureau
Jul 19, 2013·Journal of Surgical Oncology·Julie E LangAparna Vijayasekaran
Aug 3, 2013·Blood·Jasmijn F TimpSuzanne C Cannegieter
May 20, 2015·Journal of Thrombosis and Haemostasis : JTH·Y HisadaN Mackman
Sep 10, 2016·Thrombosis and Haemostasis·Corinne Frere, Dominique Farge
Oct 27, 2016·Plastic and Reconstructive Surgery·Joseph A RicciMatthew L Iorio

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Citations

Nov 24, 2019·Journal of Surgical Oncology·T N Diem VuJames W Jakub
May 27, 2020·Plastic and Reconstructive Surgery·Danielle H RochlinArash Momeni
Apr 27, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Rakel M ZarbKarri A Adamson

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