Venous thromboembolism and its prophylaxis in elective total hip arthroplasty: an international perspective

Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
Aswin ChariHemant Pandit

Abstract

Patients undergoing total hip arthroplasty (THA) are at high risk of developing post-operative deep vein thrombosis (DVT) or a subsequent pulmonary embolus (PE). Despite best efforts, the best prophylaxis for thromboembolic disease remains controversial. This article aims to update the reader on the newest guidelines concerning venous thromboembolism (VTE) prophylaxis for elective THAs, considering their advantages and disadvantages and highlighting their inconsistencies. The Medline database and the Internet were searched for VTE prophylaxis guidelines in English. Nine guidelines were found and compared. The comparison looked at the recommendations made, the grade of recommendation, the level of evidence available for these recommendations and any inconsistencies between the guidelines. All guidelines advocate the use of LMWH and almost all advocate the use of mechanical methods of prophylaxis. The recommended duration ranges from 7-35 days and in many cases, the duration is not specified. There is little consensus in terms of other recommended drugs, the doses, duration and their recommendation grades. There is still uncertainty about the optimal methods of thromboprophylaxis in elective total hip arthroplasty. Although there...Continue Reading

References

Aug 13, 2002·Current Opinion in Pulmonary Medicine·Richard H White, Mark C Henderson
Oct 11, 2007·The Journal of Arthroplasty·Javad ParviziRichard H Rothman
May 2, 2009·The Journal of Bone and Joint Surgery. British Volume·L A Cusick, D E Beverland

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Citations

Sep 4, 2015·Acta ortopedica brasileira·Flávio Luís GarciaCelso Hermínio Ferraz Picado
Feb 24, 2015·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Scott YangQuanjun Cui
May 31, 2018·Acta ortopedica brasileira·Raul Carneiro LinsFlávio Kreimer
Feb 14, 2020·BMC Musculoskeletal Disorders·Viswanath MulaMahbub Alam
Jun 17, 2021·BMC Musculoskeletal Disorders·Xinyan YuRende Ning

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