Venous Thromboembolism in Patients With Spontaneous Intracerebral Hemorrhage: A Multicenter Study

Neurosurgery
Dale DingJennifer Osborne

Abstract

Patients with spontaneous intracerebral hemorrhage (ICH) are predisposed to venous thromboembolic (VTE) complications, such as deep vein thrombosis and pulmonary embolism. To evaluate, in a multicenter, retrospective cohort study, the rate of VTE complications in ICH patients during acute hospitalization, identify potential risk factors, and assess their association with functional outcome. We retrospectively analyzed prospectively collected data from 19 centers and 41 sites that participated in the Ethnic/Racial Variations of Intracerebral Hemorrhage study, from August 2010 to February 2016. We compared ICH patients with VTE complications to those without VTE complications. Statistical analyses were performed to determine predictors of VTE complications and poor outcome (modified Rankin Scale ≥ 4) at discharge and 3-mo follow-up. Of the 2902 ICH patients who were eligible for analysis, 87 (3.0%) had VTE complications: 57 (2.0%) had only deep vein thrombosis, 19 (0.7%) had only pulmonary embolism, and 11 (0.4%) had both. In the multivariable logistic regression analysis, a prior history of VTE (odds ratio [OR] = 6.8; P < .0001), intubation (OR = 4.0; P < .0001), and presence of IVH (OR = 1.8; P = .0157) were independent predict...Continue Reading

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Citations

Mar 7, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Xi PanQi Fang
Sep 24, 2021·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·A I KhripunE A Luk'yanova

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