Venous Thromboembolism Prophylaxis and Risk for Acutely Medically Ill Patients Stratified by Different Ages and Renal Disease Status

Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Alpesh N AminJay Lin

Abstract

The objectives of this study were to examine venous thromboembolism (VTE) prophylaxis patterns and risk for VTE events during hospitalization and in the outpatient continuum of care among patients hospitalized for acute illnesses in the United States with stratification by different age groups and renal disease status. Acutely ill hospitalized patients were identified from the MarketScan databases (January 1, 2012-June 30, 2015) and grouped by age (<65, 65-74, ≥75 years old) and whether or not they had a baseline diagnosis of renal disease, separately. Of acutely ill hospitalized patients, 60.1% (n = 10 748) were <65 years old, 15.7% (n = 2803) were 65 to 74 years old, and 24.3% (n = 4344) were ≥75 years old; 32.9% (n = 5892) had baseline renal disease. Among the study cohorts, the majority of patients received no VTE prophylaxis regardless of age or baseline renal status (52.1%-63.6%). Rates of VTE during hospitalization and in the 6 months postdischarge were 4.7%, 4.6%, and 4.5% for patients <65, 65 to 74, and ≥75 years old, respectively, and 6.3% and 3.8% for patients with and without baseline renal disease. The risk for VTE was elevated for 30 to 40 days after index admission regardless of age and renal disease status.

References

Dec 23, 2011·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Alpesh N AminStephen Johnston
Feb 8, 2013·The New England Journal of Medicine·Alexander T CohenUNKNOWN MAGELLAN Investigators
Jul 22, 2014·Journal of Thrombosis and Haemostasis : JTH·C F ChristiansenH T Sørensen
Aug 6, 2014·European Journal of Internal Medicine·José A NietoUNKNOWN MEDITROM Investigators
May 28, 2016·The New England Journal of Medicine·Alexander T CohenUNKNOWN APEX Investigators
Dec 23, 2016·Vascular Health and Risk Management·Luiz Francisco CardosoAntonio Carlos Onofre de Lira
Jan 28, 2017·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Katharine L CheungMary Cushman
Aug 22, 2017·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·David Massicotte-AzarniouchManish M Sood

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Citations

Aug 9, 2020·Blood·Rushad PatellJeffrey I Zwicker
Oct 8, 2019·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Anne-Céline MartinAlexander T Cohen

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