Ventilation Limits Aerobic Capacity after Functional Electrical Stimulation Row Training in High Spinal Cord Injury

Medicine and Science in Sports and Exercise
Shuang QiuJ Andrew Taylor

Abstract

In the able-bodied, exercise training results in increased ventilatory capacity to meet increased aerobic demands of trained skeletal muscle. However, after spinal cord injury (SCI), peak ventilation can be limited by pulmonary muscle denervation. In fact, peak ventilation may restrict aerobic capacity in direct relation to injury level. Hybrid functional electrical stimulation (FES) exercise training results in increased aerobic capacity and dissociation between aerobic capacity and injury level in those with injuries at T3 and below. However, injuries above T3 have the greatest pulmonary denervation, and ventilatory capacity may restrict the increase in aerobic capacity with hybrid FES training. We assessed relationships among injury level, peak ventilation, and peak aerobic capacity and calculated oxygen uptake efficiency slope during hybrid FES exercise in 12 individuals (1 female) with SCI at level T2 to C4 (injury duration = 0.33-33 yr, age = 20-60 yr), before and after 6 months of FES-row training (FES-RT). Training increased peak aerobic capacity by 12% (P = 0.02) with only a modest increase in peak ventilation (7 of 12 subjects, P = 0.09). Both before and after training, injury level was directly related to peak ventil...Continue Reading

References

Dec 1, 1992·Medicine and Science in Sports and Exercise·R CasaburiK Wasserman
Oct 1, 1993·Medicine and Science in Sports and Exercise·S P HookerA R Waters
Sep 1, 1993·Medicine and Science in Sports and Exercise·J C KraussE K Lange
Jan 1, 1997·European Journal of Applied Physiology and Occupational Physiology·A VinetJ P Micallef
Jul 31, 2003·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Kazuo TsuyukiShunichirou Dohi
Jul 15, 2005·Medicine and Science in Sports and Exercise·Dick H J ThijssenMaria T E Hopman
May 23, 2009·Medicine and Science in Sports and Exercise·Dick H J ThijssenMaria T E Hopman
Jan 1, 2009·Critical Reviews in Biomedical Engineering·Chelsea A Pelletier, Audrey L Hicks
Mar 11, 2011·American Journal of Physical Medicine & Rehabilitation·Berit BrurokJan Hoff
Jun 23, 2011·European Journal of Applied Physiology·Xing-Guo SunWilliam W Stringer
Aug 3, 2011·Medicine and Science in Sports and Exercise·Sophie Antoine-JonvilleMark J Dayer
Sep 29, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·J Andrew TaylorJeffrey J Widrick
May 21, 2013·Medicine and Science in Sports and Exercise·Nazirah HasnanGlen M Davis
Jan 9, 2014·American Journal of Physical Medicine & Rehabilitation·Maya BattikhaJ Andrew Taylor
Aug 26, 2014·European Journal of Preventive Cardiology·Roselien BuysVéronique A Cornelissen
Aug 26, 2014·Archives of Physical Medicine and Rehabilitation·J Andrew TaylorGaelle Deley

❮ Previous
Next ❯

Citations

May 18, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Mariana Cardoso MeloAlcimar Barbosa Soares
Feb 7, 2018·American Journal of Physical Medicine & Rehabilitation·Rebecca F ShafferJ Andrew Taylor
Mar 2, 2018·Journal of Applied Physiology·James W MorganIsabelle Vivodtzev
Dec 23, 2020·Journal of Cardiopulmonary Rehabilitation and Prevention·Isabelle Vivodtzev, J Andrew Taylor
May 2, 2017·Autonomic Neuroscience : Basic & Clinical·Sebastian Cruz, Cheri A Blauwet

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.