PMID: 8448291Jan 1, 1993Paper

Ventricular CSF shunt infections associated with Corynebacterium jeikeium: report of three cases and review

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
K A GreeneJ M Zabramski

Abstract

Ventricular CSF shunt infections due to Corynebacterium jeikeium are rare. Such infections may become manifest weeks to months after surgery. They are difficult to eradicate and often recur. We report three cases of C. jeikeium ventricular CSF shunt infections, all of which occurred in patients who received long-term prophylactic therapy with antibiotics and had protracted hospitalizations. Two patients had multiple recurrences, and all patients required shunt revision. Additional therapy with intrathecal vancomycin for 6-10 days after surgery was effective for this unusual cause of ventricular CSF shunt infection. On the basis of our experience and a review of six previously published case reports, we recommend CSF sterilization with intravenous and intrathecal vancomycin, followed by replacement of shunt hardware.

Citations

Sep 2, 1999·Infectious Disease Clinics of North America·A Morris, D E Low
Jan 10, 2002·Infectious Disease Clinics of North America·R B Thomson, H Bertram
Sep 3, 2010·Journal of Neurosurgery. Pediatrics·Tamara D SimonJay Riva-Cambrin
Jun 10, 2014·Brain Injury : [BI]·Flávio Key MiuraAntonio Carlos Nicodemo
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