Abstract
Ectopy-mediated cardiomyopathy (EMC) is a potentially reversible form of left ventricular systolic dysfunction. Various risk factors for the development of EMC have been proposed in the literature. We aim to assess medium term outcomes of focal ventricular arrhythmia (VA) ablation in the setting of cardiomyopathy (CMP) and to validate published risk factors for EMC. Medium term recovery of left ventricular (LV) function and freedom from VA recurrence was assessed and compared between patients undergoing focal VA ablation in the setting of CMP and a control group with normal LV function. Univariate and multivariate analyses for CMP risk factors were performed and compared against prior published risk factors. Of 152 patients who underwent 170 focal VA ablation procedures, 54 (36%) had CMP and the remaining 98 patients had normal LV systolic function. At medium term follow-up, 85% of patients with CMP were free of VA recurrence and median left ventricular ejection fraction (LVEF) had improved from 40 to 52%. Age, male gender, premature ventricular complex (PVC) burden, non- right ventricular outflow tract (RVOT) sites of origin, PVC QRS duration and PVC minimum coupling interval were predictive of CMP on univariate analysis, but ...Continue Reading
Citations
Jun 5, 2019·Circulation. Arrhythmia and Electrophysiology·Robert D AndersonGeoffrey Lee
May 11, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Edmond M CroninUNKNOWN ESC Scientific Document Group
Sep 23, 2019·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Bernas Altıntaşİbrahim Halil Tanboğa
Apr 28, 2020·Circulation·Gregory M Marcus
Mar 17, 2020·Current Opinion in Cardiology·Aleksandr Voskoboinik, Joshua D Moss
Jan 22, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Edmond M CroninKatja Zeppenfeld
Jan 28, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Edmond M CroninKatja Zeppenfeld
Jan 30, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Edmond M CroninKatja Zeppenfeld
Feb 18, 2020·Heart, Lung & Circulation·Harry G Mond, Haris M Haqqani
Apr 16, 2021·Progress in Cardiovascular Diseases·Jose F HuizarKenneth A Ellenbogen
May 28, 2019·JACC. Clinical Electrophysiology·Rakesh Latchamsetty, Frank Bogun
May 28, 2021·Journal of Cardiovascular Electrophysiology·Sung-Il ImEdward P Gerstenfeld
May 29, 2021·International Journal of Cardiology·Adam C LeeHaris M Haqqani