PMID: 1201569Sep 1, 1975Paper

Ventricular fibrillation threshold and vulnerable period in the isolated perfused rat heart

Cardiovascular Research
W F LubbeC Marzagao

Abstract

Ventricular fibrillation threshold (VFT) measurements were obtained in the isolated perfused rat heart. Detailed morphology of the vulnerable period (VP) could be described by stimulating repeatedly at increasing levels of stimulus energy. Addition of lignocaine to the system caused an elevation of VGT, but also led to a delay of the VP to the end of the QT interval. The implications of these findings for the understanding of VFT measurements are discussed.

Citations

Dec 1, 1992·Cardiovascular Drugs and Therapy·M G Worthington, L H Opie
Jan 1, 1984·Pharmacology & Therapeutics·E Winslow
Jun 1, 1992·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·M F PerkinK J LaMarque
Sep 1, 1983·Annals of Surgery·F G LeicherW G Austen
Nov 1, 1981·Journal of Pharmacological Methods·B Woodward
Mar 1, 1979·The American Journal of Cardiology·W F LubbeL H Opie

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