Ventricular pacing in single ventricles-A bad combination

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Anica BulicAnne M Dubin

Abstract

Chronic ventricular pacing (VP) is associated with systolic dysfunction in a subset of pediatric patients with heart block and structurally normal hearts. The effect of chronic VP in congenital heart disease is less well understood, specifically in the single-ventricle (SV) population. To determine the longitudinal effect of VP in SV patients. SV patients with heart block and dual-chamber pacemakers requiring >50% VP were compared with nonpaced (controls) SV patients matched for age, sex, and SV morphology. Patients were excluded if a prepacing echocardiogram was not available. Echocardiogram and clinical parameters were compared at baseline (prepacing) and at last follow-up in the paced group, and in controls when they were at ages similar to those of their paced-group matches. Twenty-two paced and 53 control patients from 2 institutions were followed for similar durations (6.6±5 years vs 7.6±7.6 years; P = .59). There was no difference between groups regarding baseline ventricular function or the presence of moderate-to-severe atrioventricular valvar regurgitation (AVVR). Paced patients were more likely to develop moderate-to-severe systolic dysfunction (68% vs 15%; P < .01) and AVVR (55% vs 8%; P < .001) and require heart fa...Continue Reading

Citations

Jul 2, 2019·Circulation·Jack RychikUNKNOWN American Heart Association Council on Cardiovascular Disease in the Young and Council on Cardiovascular and Stroke Nursing
Dec 29, 2020·Open Heart·Benjamin M MooreRachael L Cordina
Mar 10, 2021·Pacing and Clinical Electrophysiology : PACE·Peter A ZartnerSven Dittrich
Jun 8, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Elizabeth A Stephenson

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