Ventricular tachycardia in arrhythmogenic right ventricular dysplasia/cardiomyopathy: clinical presentation, risk stratification and results of long-term follow-up

International Journal of Cardiology
Thomas PezawasHerwig Schmidinger

Abstract

Not all patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) are at risk for sudden cardiac death. The aim of the study was to evaluate the risk stratification in patients with ARVD/C. Programmed ventricular stimulation (PVS) was performed in 34 ARVD/C patients. Twenty-two, 7 and 4 patients had documented sustained monomorphic ventricular tachycardia (smVT), non-smVT and ventricular fibrillation, respectively. One patient experienced syncope only. An implantable cardioverter defibrillator (ICD) was implanted in 11 patients inducible in smVT with hemodynamic compromise, in 4 patients with documented ventricular fibrillation and in one patient with non-smVT (194 ms tachycardia cycle length) (ICD group, n = 16). Ten patients were left without any antiarrhythmic therapy, 5 patients received antiarrhythmic drugs and 3 patients underwent successful VT ablation (non-ICD group, n = 18). Thirteen patients had an abnormal signal averaged ECG. During 6.5 +/- 2.4 years 69% of ICD patients received appropriate discharges and one non-ICD patient had a hemodynamically tolerated smVT recurrence (no sudden cardiac death in both groups). Comparison between the cycle lengths of clinical VT, induced VT and follow-up VT ...Continue Reading

References

Nov 1, 1988·Journal of the American College of Cardiology·A NavaG Fasoli
Jan 21, 1988·The New England Journal of Medicine·G ThieneN Pennelli
Jul 21, 1988·The New England Journal of Medicine
Mar 1, 1987·American Heart Journal·M LaurentJ C Daubert
Feb 1, 1982·Circulation·F I MarcusY Grosgogeat
Mar 1, 1995·Journal of the American College of Cardiology·L DalientoG Thiene
Feb 25, 1998·Pacing and Clinical Electrophysiology : PACE·F FurlanelloS Chierchia
Apr 24, 1999·The American Journal of Cardiology·P TurriniA Nava
Mar 20, 2004·Journal of Cardiovascular Electrophysiology·Chandra BommaHugh Calkins
May 18, 2004·Journal of the American College of Cardiology·Ariel RoguinHugh Calkins
Oct 27, 2004·The American Journal of Medicine·Srijita Sen-ChowdhryWilliam J McKenna

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Citations

May 28, 2010·Herzschrittmachertherapie & Elektrophysiologie·K WasmerL Eckardt
May 14, 2014·International Journal of Cardiology·Ying-Chieh LiaoShih-Ann Chen
Oct 12, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Ganesh S KamathJonathan S Steinberg
Sep 20, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Louise R A Olde NordkampJoris R de Groot
Apr 21, 2009·Transplantation Proceedings·A I FiorelliN A G Stolf
Jun 7, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andrew E EpsteinUNKNOWN Society of Thoracic Surgeons
Dec 25, 2007·Progress in Cardiovascular Diseases·Gianfranco BujaGaetano Thiene
Jan 27, 2007·International Journal of Cardiology·Yongkeun ChoWee-Hyun Park
Jul 16, 2009·Pacing and Clinical Electrophysiology : PACE·Robert M Hamilton
Jul 1, 2009·Journal of Cardiovascular Electrophysiology·Adrianus P WijnmaalenKatja Zeppenfeld
Aug 23, 2012·Journal of Cardiovascular Electrophysiology·Frank I Marcus, Aiden Abidov
Feb 6, 2010·Journal of Cardiovascular Electrophysiology·Elena Arbelo, Mark E Josephson
May 31, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Thomas P MastMaarten J Cramer
Apr 22, 2015·Cardiovascular Drugs and Therapy·Ilaria RigatoGaetano Thiene
Jun 14, 2013·Clinical Medicine Insights. Cardiology·Jorge RomeroRichard Lucariello
Feb 6, 2008·Expert Review of Cardiovascular Therapy·Hicham Z El Masry, Anil V Yadav
Dec 22, 2009·Expert Review of Medical Devices·Christopher J McLeodSamuel J Asirvatham
Jan 20, 2017·European Journal of Clinical Investigation·Thomas PezawasHerwig Schmidinger

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