PMID: 1211217Dec 1, 1975Paper

Verapamil in the treatment of atrial tachycardia with block

Acta Medica Scandinavica
O Storstein, K H Landmark

Abstract

Atrial tachycardia (A-T) with block is easily converted as a rule to sinus rhythm by DC shock, but the recurrence rate is high. So far drug treatment of this arrhythmia has been unsatisfactory. There is no drug of choice in the treatment of A-T with block. We report on the effect of verapamil on this arrhythmia in 14 patients. Ten of them reverted to sinus rhythm, but A-T with block later recurred in 4. The best effect was found in patients with no or only minimal heart enlargement and in patients with short duration of the arrhythmia. The effect of verapamil on A-T with block may support the concept of this arrhythmia being due to atrioventricular (A-V) nodal reentry, as the main effect of verapamil is a prolongation of the effective refractory period of the A-V node.

References

Jan 1, 1972·Pflügers Archiv : European journal of physiology·M KohlhardtA Fleckenstein
Feb 1, 1974·British Heart Journal·O Storstein, K Rasmussen
Mar 11, 1972·British Medical Journal·L SchamrothC Garrett
Dec 1, 1971·Journal of Medicinal Chemistry·H M McIlhenny
Mar 1, 1970·The Journal of Physiology·G W Beeler, H Reuter
Oct 1, 1970·Circulation·J T Bigger, B N Goldreyer
Jan 1, 1960·Circulation·B LOWNH D LEVINE

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Citations

Jan 1, 1988·Annals of the New York Academy of Sciences·K Nademanee, B N Singh
Jan 1, 1978·Acta Pharmacologica Et Toxicologica·B W Johansson
Sep 1, 1983·Angiology·B N SinghG Feld

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