PMID: 8946465Nov 1, 1996Paper

Verapamil sensitive incessant ventricular tachycardia in the newborn

Pacing and Clinical Electrophysiology : PACE
A DhalaA N Pelech

Abstract

Incessant VTs in infancy are often poorly tolerated. Response to conventional antiarrhythmic therapy is disappointing. The present case involves a 3-week-old infant with an incessant VT of a left bundle branch block, and normal axis morphology. This tachycardia was inducible with both atrial and ventricular pacing, but not by premature stimulation. Tachycardia persisted despite treatment with adenosine, esmolol, procainamide, and flecainide. Intravenous verapamil suppressed tachycardia and prevented inducibility, and no further recurrences were seen on oral verapamil. This case suggests that some incessant VTs in infancy may be due to calcium channel related afterdepolarizations or triggered activation.

Citations

Nov 28, 2006·Pharmacotherapy·Brady S MoffettNaomi J Kertesz
Feb 27, 2013·Journal of Cardiovascular Electrophysiology·Kathryn K CollinsUNKNOWN Pediatric and Congenital Electrophysiology Society
Jun 26, 2010·Congenital Heart Disease·Conrad S P WilliamsChristopher S Snyder
Apr 2, 2008·Congenital Heart Disease·Christopher SnyderVictor Lucas
Apr 22, 2019·Archives of Disease in Childhood·Jascha KehrJonathan R Skinner

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