Verb comprehension in frontotemporal degeneration: the role of grammatical, semantic and executive components

Neurocase
Jina RheeM Grossman

Abstract

Verb comprehension has been associated with the left frontal cortex, but assessments of verb comprehension in frontotemporal degeneration (FTD) have been rare. This study assessed word-picture matching for verbs and nouns under two conditions: alone (baseline) and during concurrent performance of a secondary task. In addition, we correlated FTD patients' verb comprehension with their performance on measures of executive resources and language. We found that FTD patients were significantly less accurate and required significantly longer to make word-picture matching decisions about verbs compared with nouns at baseline. During concurrent performance of a secondary task, accuracy decreased and response latencies became prolonged for nouns to the point that these measures equaled the performance with verbs at baseline. Verb comprehension accuracy was significantly correlated with the performance on executive measures such as category naming fluency, the Stroop test, and the Trail Making Test Part B (Trails B test). Assessment of FTD patient subgroups revealed distinct profiles of performance, suggesting that several factors contribute to verb comprehension in FTD. Verb comprehension in FTD patients with a dysexecutive syndrome (EX...Continue Reading

Citations

Nov 30, 2010·International Psychogeriatrics·Maarten E H van NiekerkRichard C Oude Voshaar
Jan 1, 2006·Cognitive Neuropsychology·Phyllis KoenigMurray Grossman
Oct 19, 2011·Cognitive Neuropsychology·Agnesa Pillon, Peggy d'Honincthun
Aug 8, 2008·Journal of Clinical and Experimental Neuropsychology·Diego Fernandez-DuqueSandra E Black
Apr 19, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·M Grossman, P Moore
Apr 25, 2013·International Review of Psychiatry·Michał Harciarek, Stephanie Cosentino
Feb 3, 2004·Annals of Neurology·Argye E HillisLynda Ken
Mar 3, 2004·Annals of Neurology·Maria Luisa Gorno-TempiniBruce L Miller
Jun 18, 2015·Arquivos de neuro-psiquiatria·Inês Tello RodriguesAlexandre Castro-Caldas
May 21, 2008·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Peggy d'Honincthun, Agnesa Pillon
Nov 16, 2007·Journal of Geriatric Psychiatry and Neurology·James A Levy, Gordon J Chelune
Feb 9, 2002·Human Brain Mapping·Murray GrossmanJames Gee
Dec 20, 2007·Alzheimer Disease and Associated Disorders·Jennifer M OgarMaria Luisa Gorno-Tempini
Dec 6, 2005·Neuropsychology Review·Michal Harciarek, Krzysztof Jodzio
Dec 7, 2005·Brain : a Journal of Neurology·Thomas H BakJohn R Hodges
Aug 2, 2002·Current Opinion in Neurology·Murray Grossman
Jan 1, 2013·Dementia & Neuropsychologia·Leticia Lessa MansurRicardo Nitrini
Dec 14, 2018·Scientific Reports·Georgette D KanmogneRobert K Heaton
Feb 16, 2013·Brain Structure & Function·Juan Felipe CardonaAgustín Ibáñez
Mar 1, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sunghye ChoMark Liberman
Jun 29, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sladjana LukicMaria L Gorno-Tempini
Dec 16, 2005·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Murray GrossmanPeachie Moore
Jul 1, 2009·Journal of Neurolinguistics·Sharon AshMurray Grossman

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