Verbal memory and literacy outcomes one year after pediatric temporal lobectomy: a retrospective cohort study

Epilepsy & Behavior : E&B
Suncica Lah, Mary Lou Smith

Abstract

In children with temporal lobe epilepsy (TLE), temporal lobectomy (TL) is a treatment of choice for those children with seizure that are difficult to control with medication. Semantic memory is dependent on functional integrity of the temporal lobes and is thought to be critical for development of literacy skills. However, little is known about semantic memory and literacy outcomes post-TL in children. In this retrospective cohort study, 40 children with TLE were administered tests of memory and literacy pre-TL and 1year post-TL in one hospital between 1996 and 2011. One year post-TL, 60% of the children became seizure-free. A significant decline was found in one aspect of semantic memory (naming) in children who underwent left TL. In addition, a significant drop was also evident in one aspect of literacy (reading accuracy), irrespective of the side of surgery. These declines were related neither to each other nor to epilepsy variables including seizure outcome. This is the largest pediatric outcome study of memory and literacy skills to date and shows that TL is associated with a risk of a mild drop in specific aspects of semantic memory (naming, following left TL) and reading accuracy, while other areas of memory and literacy...Continue Reading

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Citations

May 20, 2015·Epilepsy & Behavior : E&B·Klajdi PukaMary Lou Smith
Jul 28, 2016·Epilepsy & Behavior : E&B·Klajdi Puka, Mary Lou Smith
Aug 19, 2016·Epilepsy & Behavior : E&B·Klajdi Puka, Mary Lou Smith
Jan 18, 2017·Archives of Disease in Childhood·Vijay M RavindraRobert J Bollo
Dec 7, 2018·Neurology·Marla J HambergerMary Lou Smith
Feb 25, 2019·Seizure : the Journal of the British Epilepsy Association·Linda M Gonzalez, Jacquie A Wrennall
Jul 1, 2020·Seizure : the Journal of the British Epilepsy Association·Kullasate SakpichaisakulRavindra Arya

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