Verification of modified receiver-operating characteristic software using simulated rating data

Radiological Physics and Technology
Junji ShiraishiTakeshi Hara

Abstract

ROCKIT, which is a receiver-operating characteristic (ROC) curve-fitting software package, was developed by Metz et al. In the early 1990s, it is a very frequently used ROC software throughout the world. In addition to ROCKIT, DBM-MRMC software was developed for multi-reader multi-case analysis of the difference in average area under ROC curves (AUCs). Because this old software cannot run on a PC with Windows 7 or a more recent operating system, we developed new software that employs the same basic algorithms with minor modifications. In this study, we verified our modified software and tested the differences between the index of diagnostic accuracies using simulated rating data. In our simulation model, all data were generated using target AUCs and a binormal parameter b. In ROC curve fitting with simulated rating data, we varied four factors: the total number of case samples, the ratio of positive-to-negative cases, a binormal parameter b, and the preset AUC. To investigate the differences between the statistical test results obtained from our software and the existing software, we generated simulated rating data sets with three levels of case difficulty and three degrees of difference in AUCs obtained from two modalities. As...Continue Reading

References

Oct 1, 1978·Seminars in Nuclear Medicine·C E Metz
Sep 1, 1986·Investigative Radiology·C E Metz
Jun 3, 1988·Science·J A Swets
Feb 1, 1997·Academic Radiology·D D DorfmanH Abu Dagga
May 18, 1999·Journal of Mathematical Psychology·C E Metz, X Pan
Feb 1, 1960·Radiology·L B LUSTED
Apr 22, 2008·Academic Radiology·Stephen L HillisCharles E Metz
Jan 1, 2008·Radiological Physics and Technology·Charles E Metz
Jul 6, 2012·Radiological Physics and Technology·Junji ShiraishiHiroyuki Abe
Feb 13, 2016·Nature·M Mitchell Waldrop

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