PMID: 15379018Sep 24, 2004Paper

Verification of the computational dosimetry system in JAERI (JCDS) for boron neutron capture therapy

Physics in Medicine and Biology
H KumadaT Kageji

Abstract

Clinical trials for boron neutron capture therapy (BNCT) by using the medical irradiation facility installed in Japan Research Reactor No. 4 (JRR-4) at Japan Atomic Energy Research Institute (JAERI) have been performed since 1999. To carry out the BNCT procedure based on proper treatment planning and its precise implementation, the JAERI computational dosimetry system (JCDS) which is applicable to dose planning has been developed in JAERI. The aim of this study was to verify the performance of JCDS. The experimental data with a cylindrical water phantom were compared with the calculation results using JCDS. Data of measurements obtained from IOBNCT cases at JRR-4 were also compared with retrospective evaluation data with JCDS. In comparison with phantom experiments, the calculations and the measurements for thermal neutron flux and gamma-ray dose were in a good agreement, except at the surface of the phantom. Against the measurements of clinical cases, the discrepancy of JCDS's calculations was approximately 10%. These basic and clinical verifications demonstrated that JCDS has enough performance for the BNCT dosimetry. Further investigations are recommended for precise dose distribution and faster calculation environment.

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Citations

Feb 25, 2014·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Hironobu YanagieMasazumi Eriguchi
Jul 15, 2011·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Hironobu YanagieHiroyuki Takahashi
Apr 12, 2011·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·H KumadaK Ono
Dec 19, 2014·Radiation Protection Dosimetry·Kenta TakadaAkira Matsumura
Apr 21, 2009·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Kei NakaiAkira Matsumura
May 2, 2009·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·H KoivunoroS Savolainen
Apr 28, 2009·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·H KumadaA Matsumura
Jul 26, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Minoru SuzukiKoji Ono
Aug 17, 2004·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·H KumadaA Matsumura
Aug 17, 2004·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·S YonaiY Tahara
Sep 13, 2015·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Hiroaki KumadaHideyuki Sakurai
Apr 23, 2008·Expert Opinion on Drug Delivery·Hironobu YanagiëHiroyuki Takahashi
Nov 1, 2017·Radiation Protection Dosimetry·Hiroaki KumadaTakeji Sakae
Mar 19, 2005·Physics in Medicine and Biology·Sara J GonzálezRobert G Zamenhof
Aug 28, 2021·Journal of Personalized Medicine·Yoshitaka MatsumotoHideyuki Sakurai

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