Verification of the qLabs international normalized ratio point-of-care device for monitoring of patients attending an anticoagulation clinic.

International Journal of Laboratory Hematology
N MbokotaS Louw

Abstract

In the developing world, point-of-care (POC) testing for international normalized ratio (INR) plays an important role in the monitoring of patients on long-term warfarin therapy with limited access to healthcare ensuring safe and effective anticoagulation. A newly developed POC device for INR measurement by healthcare workers is the handheld qLabs POC device® (Micropoint Biotechnologies Incorporated, Guangdong, China). The qLabs POC device® was evaluated in 262 patients attending an anticoagulation clinic with regards to accuracy and precision of the INR results. The results were compared to the results obtained on the Stago STA R Max® coagulation analyzer (Stago Diagnostica, Paris, France) on a wide range of normal and abnormal results of clinical relevance. The mean laboratory INR (2.50 ± 1.08) was significantly higher than the qLabs POC device® INR (2.38 ± 1.07) (P < .0001). The correlation coefficient (r) was .88, the slope coefficient was 1.0 (CI, 0.8-1.2), and the intercept was -0.10 (CI, -0.50 to 0.30). The mean of the differences was -0.13% (CI, -0.19 to -0.06). Dosage concordance was 85.46% and clinical agreement was 92.37%. However, clinical agreement was 42.42% in the subgroup above the target range (>3.5). The impre...Continue Reading

References

Jun 1, 1994·Annals of Internal Medicine·E M Hylek, D E Singer
Jan 11, 2005·British Journal of Haematology·Chris GardinerHannah Cohen
Oct 4, 2005·British Journal of Haematology·D A FitzmauriceUNKNOWN British Society of Haematology Taskforce for Haemostasis and Thrombosis
Dec 8, 2006·Sexually Transmitted Infections·R W PeelingA Ronald
Oct 24, 2007·Clinics in Laboratory Medicine·James H Nichols
Feb 21, 2008·American Journal of Clinical Pathology·Chris GardinerSamuel J Machin
Jul 1, 2008·Thrombosis Research·W PleschA M H P van den Besselaar
Jan 16, 2009·International Journal of Laboratory Hematology·W Plesch, A M H P van den Besselaar
Jul 14, 2010·British Journal of Haematology·David J PerrySue Mallett
Dec 18, 2013·The Lancet Infectious Diseases·Paul K DrainIngrid V Bassett
Feb 3, 2016·Biotechnology Advances·Brian M CumminsGlenn M Walker
Feb 27, 2016·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·E L BenadeE Schapkaitz
Oct 7, 2017·International Journal of Laboratory Hematology·J JoubertJ Raubenheimer

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Citations

Mar 19, 2019·Omics : a Journal of Integrative Biology·Arinao NdadzaCollet Dandara
Feb 16, 2021·British Journal of Clinical Pharmacology·Johannes P MoutonKaren Cohen

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