Versatile and expeditious synthesis of aurones via Au I-catalyzed cyclization

The Journal of Organic Chemistry
Hassina HarkatPatrick Pale

Abstract

Aurones are conveniently formed in a three-step procedure including a goldI-catalyzed cyclization of 2-(1-hydroxyprop-2-ynyl)phenols as a highly regio- and stereoselective key step. A wide diversity of derivatives can be obtained starting from substituted salicylaldehydes. Synthesis of natural 4,6,3',4'-tetramethoxyaurone and structure revision of two natural products (dalmaisione D and 4'-chloroaurone) were achieved.

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Citations

Nov 17, 2012·Inorganic Chemistry·Amit S PithadiaMi Hee Lim
Jan 1, 2008·Acta Crystallographica. Section E, Structure Reports Online·Ying FanWei Huang
Jan 1, 2008·Acta Crystallographica. Section E, Structure Reports Online·Ying FanWei Huang
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Mar 12, 2011·Chemical Reviews·A CormaMaria J Sabater

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