PMID: 8609111Feb 1, 1996Paper

Vertebral body shape as a predictor of spinal deformity in osteogenesis imperfecta

The Journal of Bone and Joint Surgery. American Volume
S IshikawaM Homma

Abstract

We analyzed forty-four patients who had osteogenesis imperfecta, in order to determine the prevalence of spinal deformities. At the time of the most recent follow-up scoliosis was present in thirty patients (68 per cent) and kyphosis, in eighteen (41 per cent). According to the classification system of Falvo et al., scoliosis progressed rapidly with growth in twelve of fifteen patients who had the congenita type of osteogenesis imperfecta and in four of thirteen who had the tarda-I type. Curves that progressed before puberty did not always continue to progress after cessation of growth. Lateral roentgenograms made at the initial examination revealed four types of vertebral body deformities: biconcave, flattened, wedged, and unclassifiable vertebrae:Biconcave vertebrae were seen characteristically in patients who had the congenita type of osteogenesis imperfecta. The presence of six biconcave vertebrae or more before puberty indicated that severe scoliosis (more than 50 degrees) was likely to develop. Biconcave vertebrae did not appear to affect the severity of kyphosis. The other types of vertebral deformities were not useful for predicting progression of spinal deformity.

References

Apr 1, 1979·Journal of Medical Genetics·D O SillenceD M Danks
Nov 1, 1983·Annals of Internal Medicine·J R Shapiro, D W Rowe
May 1, 1980·AJR. American Journal of Roentgenology·G T FonA C Thies
Jan 1, 1982·The Journal of Bone and Joint Surgery. British Volume·K Yong-Hing, G D MacEwen

❮ Previous
Next ❯

Citations

Aug 1, 1997·Acta Paediatrica Japonica; Overseas Edition·T Moriwake, Y Seino
Aug 14, 1998·Acta Orthopaedica Scandinavica·R H EngelbertP J Helders
Dec 7, 2013·The Clinical Respiratory Journal·Lena L WekreErik F Eriksen
Dec 4, 2015·Medicine·Marcos Vaz de LimaClaudio Santili
Jul 26, 2017·JBJS Reviews·Courtney O'DonnellSumeet Garg
Mar 21, 2008·Journal of Neurosurgery. Pediatrics·Deanna Sasaki-AdamsJames M Drake
Feb 7, 2014·The Journal of Bone and Joint Surgery. American Volume·Alireza K AnissipourPeter A Smith
Sep 7, 2018·Journal of Bone and Mineral Metabolism·Masafumi KashiiHideki Yoshikawa
Mar 7, 2019·Journal of Children's Orthopaedics·R M CasteleinUNKNOWN EPOS Spine Study Group
Mar 27, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·I Mouna Ben AmorFrank Rauch
Dec 24, 2016·The Journal of the American Academy of Orthopaedic Surgeons·Maegen J WallaceSuken A Shah
Oct 11, 2020·Regional Anesthesia and Pain Medicine·Amy R BeetheJessica K Goeller
Dec 23, 1998·Archives of Physical Medicine and Rehabilitation·R H EngelbertP J Helders
Jul 7, 1999·The Orthopedic Clinics of North America·M Kornblum, D F Stanitski
Dec 25, 2007·Neurosurgery Clinics of North America·Adam S KanterPraveen V Mummaneni

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.