Vertical transmission of sublethal granulovirus infection in the Indian meal moth, Plodia interpunctella

Molecular Ecology
J P BurdenS M Sait

Abstract

Knowledge of the mechanisms of pathogen persistence in relation to fluctuations in host density is crucial to our understanding of disease dynamics. In the case of insect baculoviruses, which are typically transmitted horizontally via a lifestage that can persist outside the host, a key issue that remains to be elucidated is whether the virus can also be transmitted vertically as a sublethal infection. We show that RNA transcripts for the Plodia interpunctella GV granulin gene are present in a high proportion of P. interpunctella insects that survive virus challenge. Granulin is a late-expressed gene that is only transcribed after viral genome replication, its presence thus strongly indicates that viral genome replication has occurred. Almost all insects surviving the virus challenge tested positive for viral RNA in the larval and pupal stage. However, this proportion declined in the emerging adults. Granulin mRNA was also detected in both the ovaries and testes, which may represent a putative mechanism by which reduced fecundity in sublethally affected hosts might be manifested. RNA transcripts were also detected in 60-80% of second-generation larvae that were derived from mating surviving adults, but there was no difference b...Continue Reading

References

Jun 1, 1985·The Journal of General Virology·R ChakerianG S Beaudreau
Jan 1, 1983·Advances in Virus Research·R A ConsigliL A Bulla
Jan 11, 1984·Nucleic Acids Research·J DevereuxO Smithies
Jun 3, 1998·Virus Genes·C GotoS Maeda
Sep 16, 1999·Journal of Invertebrate Pathology·B Kukan
Mar 12, 2004·Annual Review of Entomology·F Moscardi

❮ Previous
Next ❯

Citations

Mar 28, 2009·Proceedings. Biological Sciences·Ian SorrellMike Boots
Mar 28, 2009·Proceedings. Biological Sciences·Mark P ZwartWopke Van der Werf
Mar 5, 2005·Applied and Environmental Microbiology·Ana-Mabel MartínezPrimitivo Caballero
Aug 14, 2013·PloS One·Cristina VirtoTrevor Williams
Nov 28, 2007·Izvestiia Akademii nauk. Seriia biologicheskaia·A V Il'inykh
Jan 31, 2007·Journal of Theoretical Biology·E O JonesM Boots
Mar 20, 2010·Evolution; International Journal of Organic Evolution·Edward O JonesMichael Boots
Apr 17, 2016·Integrative and Comparative Biology·Beth Okamura
Jun 28, 2002·BMC Evolutionary Biology·Stefan Van Dongen, Luc Lens
Aug 17, 2014·Journal of Invertebrate Pathology·Cristina VirtoPrimitivo Caballero
May 8, 2016·The Journal of Animal Ecology·Elizabeth M RedmanJenny S Cory
Sep 3, 2019·Frontiers in Immunology·Guillaume TetreauYannick Moret
Aug 5, 2017·Frontiers in Microbiology·Trevor WilliamsPrimitivo Caballero
Mar 16, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Janis AntonovicsJoanne P Webster
Jul 12, 2007·The Journal of General Virology·Constanze YueElke Genersch

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.