Very early-onset inflammatory bowel disease in Japan: A nationwide survey.

Journal of Gastroenterology and Hepatology
Takahiro KudoToshiaki Shimizu

Abstract

Very early-onset inflammatory bowel disease is defined as inflammatory bowel disease diagnosed before 6 years of age. Very early-onset inflammatory bowel disease has various differential diagnoses, including primary immunodeficiency disorders, and is known to be resistant to conventional treatment. Therefore, global attention is required to manage this challenging condition. We conducted a retrospective epidemiological survey of the number of patients, final diagnosis, and examinations performed to diagnose very early-onset inflammatory bowel disease in Japan. A primary questionnaire about the number of very early-onset bowel disease cases and its diagnosis was administered to 630 pediatric facilities nationwide in Japan. A secondary survey about the examinations performed to achieve diagnosis was sent to the facilities that responded to the first survey. The answering rate was 92.2% (581/630 facilities); 81 facilities had 225 very early-onset bowel disease patients undergoing their care during the past 68 months. Twenty-six patients (11.6%) were diagnosed with immunodeficiency-associated inflammatory bowel disease. The answering rate of the secondary survey was 70.4% (57/81 facilities). Colonoscopy, esophagogastroduodenoscopy,...Continue Reading

References

Jun 22, 2010·Inflammatory Bowel Diseases·Eric I BenchimolAnne M Griffiths
Jun 26, 2012·Gastroenterology·Aleixo M MuiseSubra Kugathasan
Dec 12, 2012·Journal of Gastroenterology and Hepatology·Shun-Ichi MaisawaAtsushi Yoden
Jul 1, 2014·Journal of Pediatric Gastroenterology and Nutrition·Oren LedderWinita Hardikar
Jul 25, 2014·Gastroenterology·Holm H UhligUNKNOWN COLORS in IBD Study Group and NEOPICS
Feb 11, 2015·Diseases of the Colon and Rectum·Tara M ConnellyWalter A Koltun
Apr 22, 2015·Inflammatory Bowel Diseases·Christopher J MoranScott B Snapper
Aug 11, 2015·Gastroenterology·Dermot McGovernJudy H Cho
Nov 26, 2015·World Journal of Gastroenterology : WJG·Anna Monica BiancoAlberto Tommasini
Apr 23, 2016·Inflammatory Bowel Diseases·Abdulrahman Al-HussainiMohammed Al-Edreesi
Apr 26, 2016·Przegla̜d gastroenterologiczny·Edyta SzymańskaJarosław Kierkuś
Jun 2, 2016·Expert Review of Clinical Immunology·Teresa CapriatiAntonella Diamanti
Jun 24, 2017·Middle East Journal of Digestive Diseases·Shahram Nemati, Shahram Teimourian
Jul 13, 2017·Current Opinion in Pediatrics·Judith R Kelsen, Robert N Baldassano
Jul 26, 2017·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Mariela DoreManuel López Santamaría
Aug 18, 2017·Current Opinion in Allergy and Clinical Immunology·Sara Ciullini Mannurita, Eleonora Gambineri
Sep 21, 2017·Inflammatory Bowel Diseases·Britt-Sabina PetersenBodo Grimbacher

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