Very low birth weight infant care: adherence to a new nutrition protocol improves growth outcomes and reduces infectious risk.

Early Human Development
Beatrice M StefanescuJennifer L Kosinski

Abstract

Very low birth weight (VLBW) infants are at risk for postnatal growth restriction due to inadequate nutrient delivery and concomitant illness. Integrated clinical pathways or protocols can improve growth outcomes by decreasing practice variability. A comprehensive nutrition bundle comprising standardized recommendations for initiating, advancing, and fortifying enteral feedings, and timely discontinuation of central lines was implemented in July 2012. Eligible were infants with a birth weight of <1500 g and <34 weeks gestation who were born over a 1-year period pre- and post-intervention, respectively. The primary aim was to determine if the intervention improved anthropometric parameter delta z scores at 36 weeks PMA. Secondary aims included time to first and full enteral feedings, central line-days, and rates of necrotizing enterocolitis (NEC) and sepsis/sepsis-like episodes. A total of 299 infants were included, of which 156 received the proposed intervention (Nutrition bundle group), and 143 received non-standardized nutrition practices (Conventional group). Median delta z scores for length (-1.2 versus -1.71; p=0.01) and head circumference (-0.73 versus -1.21; p=0.03) but not weight at 36 weeks PMA (-1.42 versus -1.58; p=0...Continue Reading

References

Jul 25, 1991·The New England Journal of Medicine·M HackE Borawski
Oct 1, 1994·Archives of Disease in Childhood·A Lucas
Sep 19, 2003·Journal of Perinatology : Official Journal of the California Perinatal Association·Kimberly D ErnstDavid H Adamkin
Jun 24, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·O Flidel-RimonE S Shinwell
Aug 24, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·R J CookeA C Fenton
Apr 30, 2005·Journal of Perinatology : Official Journal of the California Perinatal Association·Alan Lucas
Mar 25, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·Catherine A BoydPeter Brocklehurst
Jul 25, 2006·Seminars in Perinatology·Manoj A Biniwale, Richard A Ehrenkranz
Feb 15, 2007·European Journal of Clinical Nutrition·T R Fenton, R S Sauve
Nov 26, 2013·Seminars in Fetal & Neonatal Medicine·Jae H Kim
Mar 13, 2014·Early Human Development·Emily HamiltonSarah Taylor
Sep 30, 2014·The Journal of Pediatrics·Sara SammallahtiKatri Räikkönen
Apr 17, 2015·Journal of Perinatology : Official Journal of the California Perinatal Association·P D GrazianoM J Horgan

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Citations

Dec 22, 2016·Nutrients·Anke Raaijmakers, Karel Allegaert
Feb 15, 2017·JPEN. Journal of Parenteral and Enteral Nutrition·Carmen A CunninghamBodil M K Larsen
Mar 31, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·B Jasani, S Patole
Apr 11, 2017·Korean journal of pediatrics·Joon-Sik ParkRan Namgung
Nov 14, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Fangwen HuWei Cai
Oct 26, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·J M MeyersUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Aug 20, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Atoosa F CraigheadDmitry Dukhovny
May 10, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Sarah U MortonSusanna Y Huh
Jan 12, 2019·International Journal of Pediatrics·Pasqua Anna QuitadamoPierpaolo Cristalli
May 21, 2020·Journal of Perinatal Medicine·María Del Mar Fernández-MartínezAntonio Bonillo-Perales
Aug 30, 2019·Paediatrics & Child Health·James Haiyang XuUNKNOWN Canadian Neonatal Network Investigators
Nov 6, 2020·Archives of Disease in Childhood. Fetal and Neonatal Edition·Dustin D FlanneryUNKNOWN Postnatal Growth and ROP (G-ROP) Study Group
Feb 15, 2018·Pediatrics·Juliane SchneiderSteven P Miller

❮ Previous
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