Very low embryonic crude oil exposures cause lasting cardiac defects in salmon and herring

Scientific Reports
John P IncardonaNathaniel L Scholz

Abstract

The 1989 Exxon Valdez disaster exposed embryos of pink salmon and Pacific herring to crude oil in shoreline spawning habitats throughout Prince William Sound, Alaska. The herring fishery collapsed four years later. The role of the spill, if any, in this decline remains one of the most controversial unanswered questions in modern natural resource injury assessment. Crude oil disrupts excitation-contraction coupling in fish heart muscle cells, and we show here that salmon and herring exposed as embryos to trace levels of crude oil grow into juveniles with abnormal hearts and reduced cardiorespiratory function, the latter a key determinant of individual survival and population recruitment. Oil exposure during cardiogenesis led to specific defects in the outflow tract and compact myocardium, and a hypertrophic response in spongy myocardium, evident in juveniles 7 to 9 months after exposure. The thresholds for developmental cardiotoxicity were remarkably low, suggesting the scale of the Exxon Valdez impact in shoreline spawning habitats was much greater than previously appreciated. Moreover, an irreversible loss of cardiac fitness and consequent increases in delayed mortality in oil-exposed cohorts may have been important contributo...Continue Reading

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Citations

Dec 15, 2015·Environmental Science & Technology·Jenifer McIntyreNathaniel Scholz
May 14, 2016·Environmental Science & Technology·Danielle A PhilibertKeith B Tierney
Jun 15, 2016·Marine Pollution Bulletin·Lindsey DornbergerFelicia Coleman
Jul 23, 2016·Aquatic Toxicology·John P Incardona, Nathaniel L Scholz
Mar 29, 2016·Environmental Toxicology and Chemistry·John D StieglitzMartin Grosell
Jun 23, 2016·Environmental Toxicology and Chemistry·Sarah L AldermanTodd E Gillis
Jul 30, 2016·Rapid Communications in Mass Spectrometry : RCM·Lisbet SørensenSvein A Mjøs
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May 20, 2020·Conservation Biology : the Journal of the Society for Conservation Biology·Christopher G GoodchildSarah E DuRant
Jul 12, 2017·Archives of Environmental Contamination and Toxicology·John P Incardona
Feb 5, 2021·Marine Pollution Bulletin·Jörundur SvavarssonHalldór Pálmar Halldórsson
Dec 24, 2018·The Science of the Total Environment·Denby McDonnellValerie S Langlois
Jan 30, 2021·Environmental Toxicology and Chemistry·G A BurtonE Scharberg
Sep 18, 2018·Chemosphere·Jeffrey M MorrisJohn P Incardona
Feb 2, 2021·Environmental Toxicology and Chemistry·Victoria McGruerDaniel Schlenk
Apr 18, 2021·Scientific Reports·Morgan Lizabeth BenderJasmine Nahrgang
May 26, 2021·Environmental Science & Technology·Alexis J KhursigaraAndrew J Esbaugh
Jun 30, 2021·Arhiv za higijenu rada i toksikologiju·Tarek Fakhereddin, Demet Doğan

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