Vesicoureteral refux detection in children: a comparison of the midline-to-orifice distance measurement by ultrasound and voiding urosonography

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Nina BattelinoTanja Kersnik Levart

Abstract

Due to the questionable clinical role of vesicoureteral reflux (VUR) and the search for noninvasive, radiation-free procedures sufficiently reliable to detect VUR, we compared the correlation between the midline-to-orifice distance (MOD) measured by ultrasonography (US) and echo-enhanced voiding urosonography (VUS) for detecting VUR in children. The aim of the study was to determine whether measuring MOD by US could be a reliable predictor of VUR in children. A total of 116 children, aged 0.25-84 months, with 232 potentially refluxing units were investigated simultaneously by measuring the MOD and performing VUS. Indications for cystography were urinary tract infection and follow-up of a previously detected VUR. VUS was performed after the MOD measurement. The results were analyzed with VUS as the reference method. The MOD was significantly larger in VUR grade III (10.7 mm; p = 0.003) and VUR grade II (9.9 mm; p = 0.001) refluxing units than in non-refluxing units (7.8 mm), even when controlling for the estimated volume/expected maximal capacity (Vest/Vmax) ratio. A MOD cutoff value of 7.4 mm was chosen as a predictor of either the presence or absence of VUR; the sensitivity and specificity of this cutoff measurement for VUR de...Continue Reading

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Citations

Oct 6, 2017·Abdominal Radiology·Aikaterini NtouliaSusan J Back
Dec 21, 2018·International Journal of Urology : Official Journal of the Japanese Urological Association·Kazuyoshi JohninAkihiro Kawauchi
Apr 1, 2021·Pediatric Radiology·Aikaterini NtouliaFrederica Papadopoulou
Oct 31, 2021·Pediatric Radiology·Aikaterini NtouliaKassa Darge

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